Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 13/20 | 0.61 |
| ▸ | CTRB1 | P17538 | 5/20 | 0.61 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | LCK | P06239 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6499066 | 0.93 | ELANE (0.64) | ELANECTRB1 | |
| SCHEMBL7838428 | 0.92 | ELANE (0.61) | ELANECTRB1 | |
| SCHEMBL7837321 | 0.92 | ELANE (0.70) | ELANECTRB1KLK5ALDH1A1LMNA | |
| SCHEMBL7839374 | 0.90 | ELANE (0.59) | ELANECTRB1KLK5LCK | |
| SCHEMBL7840236 | 0.89 | ELANE (0.59) | ELANECTRB1KLK5LCK | |
| SCHEMBL6498011 | 0.85 | ELANE (0.63) | ELANECTRB1 | |
| SCHEMBL6496223 | 0.85 | ELANE (0.72) | ELANECTRB1ALDH1A1LMNATP53 | |
| SCHEMBL6503996 | 0.83 | ELANE (0.60) | ELANECTRB1LCK | |
| SCHEMBL6498666 | 0.83 | ELANE (0.62) | ELANECTRB1LCK | |
| SCHEMBL6800825 | 0.82 | ELANE (0.61) | ELANECTRB1LCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0828721-B1 | 2-AMINO-BENZOXAZINONES FOR THE TREATMENT OF VIRAL INFECTIONS | SEARLE & CO (US) | 2001-11-14 | — | — | EP | claimed |