Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR2 | Q9NS75 | 5/20 | 0.59 |
| ▸ | CYSLTR1 | Q9Y271 | 5/20 | 0.59 |
| ▸ | LMNA | P02545 | 6/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.56 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.49 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.49 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.49 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.49 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.49 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.49 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.49 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.49 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7832861 | 1.00 | CYSLTR2 (0.59) | CYSLTR2CYSLTR1LMNAKDM4ELTB4R | |
| SCHEMBL7832237 | 1.00 | CYSLTR2 (0.59) | CYSLTR2CYSLTR1LMNAKDM4ELTB4R | |
| SCHEMBL7820491 | 0.96 | CYSLTR2 (0.60) | CYSLTR2CYSLTR1LMNAKDM4ELTB4R | |
| SCHEMBL7820483 | 0.96 | CYSLTR2 (0.60) | CYSLTR2CYSLTR1LMNAKDM4ELTB4R | |
| SCHEMBL8650189 | 0.95 | CYSLTR2 (0.55) | CYSLTR2CYSLTR1LMNAKDM4ELTB4R | |
| SCHEMBL8650191 | 0.95 | CYSLTR2 (0.55) | CYSLTR2CYSLTR1LMNAKDM4ELTB4R | |
| SCHEMBL7832354 | 0.85 | HDAC1 (0.64) | LMNAKDM4EMAPTSMN1; SMN2HTT | |
| SCHEMBL7829154 | 0.85 | HDAC1 (0.64) | LMNAKDM4EMAPTSMN1; SMN2HTT | |
| SCHEMBL7832648 | 0.85 | HDAC1 (0.64) | LMNAKDM4EMAPTSMN1; SMN2HTT | |
| SCHEMBL7831718 | 0.82 | CYSLTR2 (0.66) | CYSLTR2CYSLTR1LMNAKDM4ELTB4R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0737671-B1 | Aromatic hydroxamic acid compounds, their production and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2001-12-12 | — | — | EP | disclosed |
| EP-0737671-A2 | Aromatic hydroxamic acid compounds, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1996-10-16 | — | — | EP | disclosed |