Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 17/20 | 0.72 |
| ▸ | PPARA | Q07869 | 15/20 | 0.72 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.66 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.57 |
| ▸ | KDR | P35968 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6158389 | 1.00 | PPARG (0.72) | PPARGPPARAFFAR1ALOX5KDR | |
| SCHEMBL6158396 | 1.00 | PPARG (0.72) | PPARGPPARAFFAR1ALOX5KDR | |
| SCHEMBL4054575 | 0.88 | PPARG (0.75) | PPARGPPARAFFAR1KDR | |
| SCHEMBL4054572 | 0.88 | PPARG (0.75) | PPARGPPARAFFAR1KDR | |
| SCHEMBL6158357 | 0.88 | PPARG (0.75) | PPARGPPARAFFAR1KDR | |
| SCHEMBL6157774 | 0.87 | PPARG (0.68) | PPARGPPARAFFAR1 | |
| SCHEMBL4057645 | 0.87 | PPARG (0.68) | PPARGPPARAFFAR1 | |
| SCHEMBL4057652 | 0.87 | PPARG (0.68) | PPARGPPARAFFAR1 | |
| SCHEMBL6158259 | 0.87 | PPARG (0.68) | PPARGPPARAFFAR1KDR | |
| SCHEMBL6158262 | 0.87 | PPARG (0.68) | PPARGPPARAFFAR1KDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1077957-A1 | OXYIMINOALKANOIC ACID DERIVATIVES WITH HYPOGLYCEMIC AND HYPOLIPIDEMIC ACTIVITY | Takeda Chemical Industries, Ltd. (JP) | 2001-02-28 | — | — | EP | disclosed |
| WO-1999058510-A1 | OXYIMINOALKANOIC ACID DERIVATIVES WITH HYPOGLYCEMIC AND HYPOLIPIDEMIC ACTIVITY | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1999-11-18 | — | — | WO | disclosed |