Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5126430 | 0.84 | HPGD (0.74) | HPGDMAPK1 | |
| SCHEMBL7840035 | 0.84 | MEN1 (0.71) | HPGD | |
| SCHEMBL12501015 | 0.84 | MEN1 (0.49) | HPGD | |
| SCHEMBL7839293 | 0.84 | TYMP (0.52) | HPGD | |
| SCHEMBL5123986 | 0.83 | HPGD (0.72) | HPGDMAPK1 | |
| SCHEMBL5117502 | 0.83 | HPGD (0.72) | HPGDMAPK1 | |
| SCHEMBL14232070 | 0.83 | HPGD (0.72) | HPGDMAPK1 | |
| SCHEMBL3996660 | 0.83 | HPGD (1.00) | HPGDMAPK1 | |
| SCHEMBL14208529 | 0.82 | HPGD (0.70) | HPGDMAPK1 | |
| SCHEMBL592220 | 0.81 | HPGD (0.48) | HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0748800-B1 | Pyrimidinedione, pyrimidinetrione, triazinedione derivatives as alpha-1-adrenergic receptor antagonists | HOFFMANN LA ROCHE (CH) | 2001-05-09 | — | — | EP | disclosed |
| US-5859014-A | USEFUL IN TREATMENT OF DISEASES INVOLVING DIRECTLY OR INDIRECTLY AN OBSTRUCTION OF THE LOWER URINARY TRACT, SUCH ASBENIGN PROSTATE HYPERPLASIA | SYNTEX (U.S.A.) INC. (US) | 1999-01-12 | — | — | US | disclosed |
| EP-0748800-A2 | Pyrimidinedione, pyrimidinetrione, triazinedione, tetrahydroquinazolinedione derivatives as alpha-1-adrenergic receptor antagonists | F. HOFFMANN-LA ROCHE AG (CH) | 1996-12-18 | — | — | EP | disclosed |