Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | ENPP1 | P22413 | 6/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | PDE2A | O00408 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4820350 | 0.87 | ENPP1 (0.36) | MAPK1ENPP1KMT2AMEN1GAA | |
| SCHEMBL14573289 | 0.84 | ENPP1 (0.38) | MAPK1ENPP1KMT2AMEN1GAA | |
| SCHEMBL4819244 | 0.83 | MAPK1 (0.38) | MAPK1ENPP1KMT2AMEN1GAA | |
| SCHEMBL14573287 | 0.82 | ENPP1 (0.39) | MAPK1ENPP1KMT2AMEN1GAA | |
| SCHEMBL4820523 | 0.82 | ENPP1 (0.36) | MAPK1ENPP1KMT2AMEN1GAA | |
| SCHEMBL7833025 | 0.81 | MAPK1 (0.44) | MAPK1ENPP1KMT2AMEN1GAA | |
| SCHEMBL7833588 | 0.81 | ENPP1 (0.36) | MAPK1ENPP1KMT2AMEN1GAA | |
| SCHEMBL4814284 | 0.81 | ENPP1 (0.35) | MAPK1ENPP1KMT2AMEN1GAA | |
| SCHEMBL6997752 | 0.80 | ENPP1 (0.37) | MAPK1ENPP1KMT2AMEN1GAA | |
| SCHEMBL14573288 | 0.79 | KMT2A (0.37) | MAPK1ENPP1KMT2AMEN1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6297251-B1 | Fungicidal trifluorophenyl-triazolopyrimidines | AMERICAN CYANAMID CO. | 2001-10-02 | — | — | US | disclosed |
| EP-0975634-B1 | FUNGICIDAL TRIFLUOROPHENYL-TRIAZOLOPYRIMIDINES | BASF AG (DE) | 2001-07-04 | — | — | EP | disclosed |
| US-6117876-A | Fungicidal trifluorophenyl-triazolopyrimidines | AMERICAN CYANAMID COMPANY (US) | 2000-09-12 | — | — | US | disclosed |