Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 18/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.38 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.38 |
| ▸ | JAK3 | P52333 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6955198 | 0.90 | MAPK14 (0.45) | MAPK14MAPTL3MBTL1 | |
| SCHEMBL6947871 | 0.90 | MAPK14 (0.45) | MAPK14MAPTL3MBTL1 | |
| SCHEMBL7805607 | 0.85 | MAPK14 (0.49) | MAPK14MAPTL3MBTL1 | |
| SCHEMBL7822968 | 0.80 | MAPK14 (0.48) | MAPK14MAPTL3MBTL1CSNK1DJAK3 | |
| SCHEMBL7078139 | 0.80 | MAPT (0.57) | MAPK14MAPTL3MBTL1CSNK1DJAK3 | |
| SCHEMBL7823149 | 0.77 | MAPK14 (0.47) | MAPK14MAPTL3MBTL1CSNK1DJAK3 | |
| SCHEMBL7819165 | 0.77 | MAPK14 (0.52) | MAPK14MAPTL3MBTL1 | |
| SCHEMBL7811422 | 0.76 | MAPK14 (0.46) | MAPK14 | |
| SCHEMBL8120061 | 0.75 | MAPK14 (0.55) | MAPK14MAPTL3MBTL1CSNK1D | |
| SCHEMBL4584929 | 0.74 | MAPK14 (0.56) | MAPK14MAPTL3MBTL1CSNK1DJAK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1014976-A4 | NOVEL SUBSTITUTED IMIDAZOLE COMPOUNDS | SMITHKLINE BEECHAM CORP (US) | 2001-08-29 | — | — | EP | claimed |
| EP-1014976-A1 | NOVEL SUBSTITUTED IMIDAZOLE COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 2000-07-05 | — | — | EP | claimed |
| WO-1999001130-A1 | NOVEL SUBSTITUTED IMIDAZOLE COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 1999-01-14 | — | — | WO | claimed |