Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 19/20 | 0.85 |
| ▸ | EGFR | P00533 | 12/20 | 0.85 |
| ▸ | KDR | P35968 | 5/20 | 0.85 |
| ▸ | CSK | P41240 | 2/20 | 0.85 |
| ▸ | ABL1 | P00519 | 10/20 | 0.72 |
| ▸ | ABL2 | P42684 | 10/20 | 0.72 |
| ▸ | CDK1 | P06493 | 6/20 | 0.72 |
| ▸ | IGF1R | P08069 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7847939 | 0.96 | SRC (0.82) | SRCEGFRKDRCSKABL1 | |
| SCHEMBL7833887 | 0.92 | SRC (0.89) | SRCEGFRKDRCSKABL1 | |
| SCHEMBL7842117 | 0.91 | SRC (0.87) | SRCEGFRKDRCSKABL1 | |
| Hydrochloric Acid SCHEMBL7844055 | 0.91 | SRC (0.98) | SRCEGFRKDRCSKABL1 | |
| SCHEMBL7833894 | 0.89 | SRC (0.84) | SRCEGFRKDRCSKABL1 | |
| SCHEMBL7846298 | 0.85 | SRC (0.75) | SRCEGFRKDRCSKABL1 | |
| SCHEMBL7834351 | 0.85 | SRC (0.78) | SRCEGFRKDRCSKABL1 | |
| SCHEMBL7847181 | 0.85 | SRC (0.87) | SRCEGFRKDRCSKABL1 | |
| SCHEMBL7847860 | 0.85 | SRC (0.81) | SRCEGFRKDRCSKABL1 | |
| SCHEMBL7845893 | 0.85 | SRC (0.73) | SRCEGFRKDRCSKABL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0783505-B1 | PYRROLO[2,3-d]PYRIMIDINES AND THEIR USE | NOVARTIS AG (CH) | 2001-03-07 | — | — | EP | disclosed |