Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.49 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.49 |
| ▸ | BRD4 | O60885 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6802248 | 0.86 | MAPT (0.52) | MAPTKCNH2MEN1KMT2A | |
| SCHEMBL6794815 | 0.86 | MAPT (0.52) | MAPTKCNH2MEN1KMT2A | |
| SCHEMBL6810386 | 0.82 | MAPT (0.49) | MAPTKCNH2MEN1KMT2A | |
| SCHEMBL7854710 | 0.82 | MAPT (0.52) | MAPTKCNH2MEN1KMT2A | |
| SCHEMBL6669830 | 0.81 | MAPT (0.49) | MAPTKCNH2MEN1KMT2A | |
| SCHEMBL6815120 | 0.80 | MAPT (0.48) | MAPTKCNH2MEN1KMT2A | |
| SCHEMBL7938457 | 0.80 | MAPT (0.67) | MAPTKCNH2MEN1KMT2A | |
| SCHEMBL6694213 | 0.79 | MAPT (0.47) | MAPTKCNH2MEN1KMT2A | |
| SCHEMBL6789243 | 0.79 | POLA1 (0.69) | KCNH2MEN1KMT2A | |
| SCHEMBL6669967 | 0.79 | KCNH2 (0.66) | KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140850-A1 | QUINOLINECARBOXAMIDES AS ANTIVIRAL AGENTS | PHARMACIA & UPJOHN COMPANY (US) | 2001-10-10 | — | — | EP | disclosed |
| US-6248739-B1 | DNA POLYMERASE INHIBITORS EFFECTIVE AGAINST HERPESVIRUSES | PHARMACIA & UPJOHN COMPANY | 2001-06-19 | — | — | US | disclosed |
| WO-2000040561-A1 | QUINOLINECARBOXAMIDES AS ANTIVIRAL AGENTS | PHARMACIA & UPJOHN COMPANY (US) | 2000-07-13 | — | — | WO | disclosed |