Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 4/20 | 0.49 |
| ▸ | TSHR | P16473 | 3/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.49 |
| ▸ | RNASEL | Q05823 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | KDR | P35968 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.43 |
| ▸ | CA12 | O43570 | 2/20 | 0.43 |
| ▸ | CA1 | P00915 | 2/20 | 0.43 |
| ▸ | CA2 | P00918 | 2/20 | 0.43 |
| ▸ | CA7 | P43166 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5168689 | 0.83 | MAPK1 (0.49) | ESR1TSHRMAPK1LMNACYP1A2 | |
| SCHEMBL6256600 | 0.75 | ESR1 (0.51) | ESR1TSHRMAPK1LMNACYP1A2 | |
| SCHEMBL23151968 | 0.74 | ESR1 (0.54) | ESR1TSHRMAPK1LMNACYP1A2 | |
| SCHEMBL17230529 | 0.73 | ESR1 (0.56) | ESR1TSHRMAPK1LMNACYP1A2 | |
| SCHEMBL9331366 | 0.72 | TSHR (0.55) | ESR1TSHRMAPK1LMNACYP1A2 | |
| SCHEMBL6426880 | 0.72 | ESR1 (0.48) | ESR1TSHRMAPK1LMNACYP1A2 | |
| SCHEMBL28486105 | 0.71 | ESR1 (0.50) | ESR1TSHRMAPK1LMNACYP1A2 | |
| SCHEMBL9634909 | 0.71 | ESR1 (0.51) | ESR1TSHRMAPK1LMNACYP1A2 | |
| SCHEMBL9132930 | 0.71 | ESR1 (0.51) | ESR1TSHRMAPK1LMNACYP1A2 | |
| SCHEMBL22283463 | 0.69 | CYP1A2 (0.46) | ESR1TSHRMAPK1LMNACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9883990-B2 | Saline nose wipe and methods of manufacture and use | LITTLE BUSY BODIES, LLC (US) | 2018-02-06 | — | — | US | disclosed |
| US-20160184192-A1 | SALINE NOSE WIPE AND METHODS OF MANUFACTURE AND USE | NEHEMIAH MFG COMPANY (US) | 2016-06-30 | — | — | US | disclosed |
| EP-1893161-B1 | MIXTURES COMPRISING ANTHRANILIC ACID AMIDES AND COOLING AGENTS AS COSMETIC AND PHARMACEUTICAL COMPOSITIONS FOR ALLEVIATING ITCHING | SYMRISE AG (DE) | 2015-08-26 | — | — | EP | disclosed |
| EP-2176067-B1 | SALINE NOSE WIPE AND METHODS OF MANUFACTURE | LITTLE BUSY BODIES LLC (US) | 2014-02-19 | — | — | EP | disclosed |
| US-8632799-B2 | Saline nose wipe and methods of manufacture and use | LITTLE BUSY BODIES, LLC (US) | 2014-01-21 | — | — | US | disclosed |
| US-20120076845-A1 | SALINE NOSE WIPE AND METHODS OF MANUFACTURE AND USE | LITTLE BUSY BODIES, INC. (US) | 2012-03-29 | — | — | US | disclosed |
| US-20120070479-A1 | SALINE NOSE WIPE AND METHODS OF MANUFACTURE AND USE | LITTLE BUSY BODIES, INC. (US) | 2012-03-22 | — | — | US | disclosed |
| US-20110207644-A1 | SALINE NOSE WIPE AND METHODS OF MANUFACTURE AND USE | LITTLE BUSY BODIES, INC. (US) | 2011-08-25 | — | — | US | disclosed |
| US-20110120486-A1 | SALINE NOSE WIPE AND METHODS OF MANUFACTURE AND USE | LITTLE BUSY BODIES, INC. (US) | 2011-05-26 | — | — | US | disclosed |
| US-7943165-B2 | Saline nose wipe and methods of manufacture and use | LITTLE BUSY BODIES, INC. (US) | 2011-05-17 | — | — | US | disclosed |
| EP-2176067-A1 | SALINE NOSE WIPE AND METHODS OF MANUFACTURE AND USE | Little Busy Bodies, Inc. (US) | 2010-04-21 | — | — | EP | disclosed |
| US-20090087465-A1 | Saline nose wipe and methods of manufacture and use | FIFTH THIRD BANK, NATIONAL ASSOCIATION | 2009-04-02 | — | — | US | disclosed |
| WO-2009023192-A1 | SALINE NOSE WIPE AND METHODS OF MANUFACTURE AND USE | LITTLE BUSY BODIES, INC. (US) | 2009-02-19 | — | — | WO | disclosed |