Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APEX1 | P27695 | 1/20 | 0.71 |
| ▸ | ATM | Q13315 | 1/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.58 |
| ▸ | HPGD | P15428 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26863271 | 0.86 | APEX1 (0.51) | APEX1ATMKDM4EHPGDSMN1; SMN2 | |
| SCHEMBL11653308 | 0.85 | KDM4E (0.67) | APEX1ATMKDM4EHPGDSMN1; SMN2 | |
| SCHEMBL14966073 | 0.83 | KDM4E (0.47) | APEX1ATMKDM4ELMNATSHR | |
| SCHEMBL6086674 | 0.80 | ATM (1.00) | APEX1ATMKDM4EHPGDSMN1; SMN2 | |
| SCHEMBL6087720 | 0.80 | ATM (0.80) | APEX1ATMKDM4EHPGDSMN1; SMN2 | |
| SCHEMBL28438637 | 0.79 | KDM4E (0.43) | APEX1ATMKDM4ELMNA | |
| SCHEMBL17637276 | 0.75 | APEX1 (0.69) | APEX1ATMKDM4EHPGDSMN1; SMN2 | |
| SCHEMBL28436076 | 0.74 | KDM4E (0.43) | ATMKDM4ELMNA | |
| SCHEMBL16209400 | 0.74 | SRD5A1 (0.46) | HPGDSMN1; SMN2 | |
| SCHEMBL14965950 | 0.74 | SRD5A1 (0.46) | HPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1091958-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2001-04-18 | — | — | EP | disclosed |
| WO-2000001692-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2000-01-13 | — | — | WO | disclosed |