Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 6/20 | 0.51 |
| ▸ | NPC1 | O15118 | 5/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | PPARG | P37231 | 1/20 | 0.47 |
| ▸ | PPARA | Q07869 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | CASP3 | P42574 | 1/20 | 0.42 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.42 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.42 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.42 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6157159 | 0.85 | PPARG (0.61) | RAB9ANPC1L3MBTL1SMN1; SMN2TDP1 | |
| SCHEMBL6157153 | 0.85 | PPARG (0.61) | RAB9ANPC1L3MBTL1SMN1; SMN2TDP1 | |
| SCHEMBL7834949 | 0.85 | PPARG (0.61) | RAB9ANPC1L3MBTL1SMN1; SMN2TDP1 | |
| SCHEMBL6157708 | 0.84 | PPARG (0.53) | RAB9ANPC1L3MBTL1SMN1; SMN2TDP1 | |
| SCHEMBL6157701 | 0.84 | PPARG (0.53) | RAB9ANPC1L3MBTL1SMN1; SMN2TDP1 | |
| SCHEMBL7834380 | 0.84 | PPARA (0.47) | TDP1MAPTPPARGPPARAMEN1 | |
| SCHEMBL7822407 | 0.82 | MAOB (0.49) | RAB9ANPC1L3MBTL1SMN1; SMN2MAPT | |
| SCHEMBL7837747 | 0.79 | PPARA (0.47) | RAB9ANPC1L3MBTL1SMN1; SMN2MAPT | |
| SCHEMBL7834925 | 0.79 | PPARG (0.53) | PPARGPPARANR1H4 | |
| SCHEMBL7834947 | 0.79 | PPARA (0.60) | PPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1077957-A1 | OXYIMINOALKANOIC ACID DERIVATIVES WITH HYPOGLYCEMIC AND HYPOLIPIDEMIC ACTIVITY | Takeda Chemical Industries, Ltd. (JP) | 2001-02-28 | — | — | EP | disclosed |
| WO-1999058510-A1 | OXYIMINOALKANOIC ACID DERIVATIVES WITH HYPOGLYCEMIC AND HYPOLIPIDEMIC ACTIVITY | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1999-11-18 | — | — | WO | disclosed |