Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 16/20 | 0.88 |
| ▸ | PPARA | Q07869 | 14/20 | 0.88 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.66 |
| ▸ | PPARD | Q03181 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | KDR | P35968 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4052840 | 1.00 | PPARG (0.88) | PPARGPPARAFFAR1PPARDMAPT | |
| SCHEMBL6157410 | 1.00 | PPARG (0.88) | PPARGPPARAFFAR1PPARDMAPT | |
| SCHEMBL4052836 | 1.00 | PPARG (0.88) | PPARGPPARAFFAR1PPARDMAPT | |
| SCHEMBL6157324 | 1.00 | PPARG (0.88) | PPARGPPARAFFAR1PPARDMAPT | |
| SCHEMBL6158990 | 1.00 | PPARG (0.88) | PPARGPPARAFFAR1PPARDMAPT | |
| SCHEMBL6157328 | 1.00 | PPARG (0.88) | PPARGPPARAFFAR1PPARDMAPT | |
| SCHEMBL6158923 | 1.00 | PPARG (0.88) | PPARGPPARAFFAR1PPARDMAPT | |
| SCHEMBL6160415 | 0.99 | PPARG (0.90) | PPARGPPARAFFAR1PPARDMAPT | |
| SCHEMBL6158370 | 0.99 | PPARG (0.90) | PPARGPPARAFFAR1PPARDMAPT | |
| SCHEMBL6158379 | 0.99 | PPARG (0.90) | PPARGPPARAFFAR1PPARDMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1077957-A1 | OXYIMINOALKANOIC ACID DERIVATIVES WITH HYPOGLYCEMIC AND HYPOLIPIDEMIC ACTIVITY | Takeda Chemical Industries, Ltd. (JP) | 2001-02-28 | — | — | EP | disclosed |
| WO-1999058510-A1 | OXYIMINOALKANOIC ACID DERIVATIVES WITH HYPOGLYCEMIC AND HYPOLIPIDEMIC ACTIVITY | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1999-11-18 | — | — | WO | disclosed |