Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.49 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.49 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 3/20 | 0.49 |
| ▸ | CA12 | O43570 | 3/20 | 0.49 |
| ▸ | CA9 | Q16790 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 2/20 | 0.48 |
| ▸ | MMP2 | P08253 | 3/20 | 0.47 |
| ▸ | MMP13 | P45452 | 3/20 | 0.47 |
| ▸ | MMP1 | P03956 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14011605 | 1.00 | GAA (0.52) | GAAKMT2ATDP1ALDH1A1LMNA | |
| SCHEMBL4040020 | 1.00 | GAA (0.52) | GAAKMT2ATDP1ALDH1A1LMNA | |
| Hydrochloric Acid SCHEMBL7347096 | 0.99 | GAA (0.51) | GAAKMT2ATDP1ALDH1A1LMNA | |
| SCHEMBL11946621 | 0.89 | CA1 (0.46) | GAAKMT2ATDP1ALDH1A1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL7346261 | 0.87 | BACE1 (0.48) | KMT2ASMN1; SMN2HSD17B10SLC1A3SLC1A2 | |
| Hydrochloric Acid SCHEMBL7346258 | 0.87 | BACE1 (0.48) | KMT2ASMN1; SMN2HSD17B10SLC1A3SLC1A2 | |
| SCHEMBL30988968 | 0.84 | GAA (0.55) | GAAKMT2ATDP1ALDH1A1LMNA | |
| SCHEMBL28560480 | 0.84 | KMT2A (0.55) | GAAKMT2ATDP1ALDH1A1LMNA | |
| SCHEMBL28554116 | 0.84 | GAA (0.55) | GAAKMT2ATDP1ALDH1A1LMNA | |
| SCHEMBL7337519 | 0.84 | TDP1 (0.63) | TDP1SLC1A3SLC1A2SLC1A1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1023295-A4 | FIBRINOGEN RECEPTOR ANTAGONIST PRODRUGS | MERCK & CO INC (US) | 2001-01-24 | — | — | EP | disclosed |
| EP-1023295-A1 | FIBRINOGEN RECEPTOR ANTAGONIST PRODRUGS | Merck & Co., Inc. (US) | 2000-08-02 | — | — | EP | disclosed |
| US-5981584-A | USEFUL IN THE MANUFACTURE OF A MEDICAMENT FOR INHIBITING THE AGGREGATION OF BLOOD PLATELETS, INHIBITING ANGIOGENESIS, INHIBITING OSTEOCLAST MEDIATED BONE RESORPTION, PREVENTING PLATELET THROMBOSIS | MERCK & CO., INC. (US) | 1999-11-09 | — | — | US | disclosed |
| WO-1998034935-A1 | FIBRINOGEN RECEPTOR ANTAGONIST PRODRUGS | MERCK & CO., INC. (US) | 1998-08-13 | — | — | WO | disclosed |