⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1483381 | 0.83 | — | — | |
| SCHEMBL125808 | 0.82 | — | — | |
| SCHEMBL7159820 | 0.80 | — | — | |
| Ammonia Solution, Strong SCHEMBL9515995 | 0.80 | TSHR (0.57) | — | |
| Hydrochloric Acid SCHEMBL30288135 | 0.80 | TSHR (0.57) | — | |
| Hydrochloric Acid SCHEMBL30807127 | 0.80 | TSHR (0.57) | — | |
| SCHEMBL13167911 | 0.80 | — | — | |
| SCHEMBL16019027 | 0.80 | — | — | |
| SCHEMBL18797494 | 0.79 | TSHR (0.50) | — | |
| SCHEMBL11025409 | 0.79 | TSHR (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0454501-B1 | Benzylidenethiazolidine derivatives, their preparation and their use for the inhibition of lipid peroxides | SANKYO CO (JP) | 2001-09-05 | — | — | EP | disclosed |
| EP-0839812-A1 | Preparation of benzylthiazolidine derivatives | Sankyo Company Limited (JP) | 1998-05-06 | — | — | EP | disclosed |
| US-5387596-A | Treating arteriosclerosis | SANKYO COMPANY, LIMITED (JP) | 1995-02-07 | — | — | US | disclosed |
| EP-0454501-A2 | Benzylidenethiazolidine derivatives, their preparation and their use for the inhibition of lipid peroxides | Sankyo Company Limited (JP) | 1991-10-30 | — | — | EP | disclosed |