Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 1/20 | 0.64 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.57 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.56 |
| ▸ | FEN1 | P39748 | 1/20 | 0.56 |
| ▸ | TNKS | O95271 | 1/20 | 0.50 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.50 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.50 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.50 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.50 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | FAAH | O00519 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | KMO | O15229 | 1/20 | 0.46 |
| ▸ | TLR4 | O00206 | 1/20 | 0.46 |
| ▸ | TLR2 | O60603 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7837384 | 1.00 | AKR1C3 (0.64) | AKR1C3HDAC8ERCC5FEN1TNKS | |
| SCHEMBL6156751 | 0.84 | AKR1C3 (0.57) | AKR1C3HDAC8ERCC5FEN1TNKS | |
| SCHEMBL6157761 | 0.84 | AKR1C3 (0.57) | AKR1C3HDAC8ERCC5FEN1TNKS | |
| SCHEMBL6156757 | 0.84 | AKR1C3 (0.57) | AKR1C3HDAC8ERCC5FEN1TNKS | |
| SCHEMBL9315114 | 0.79 | AKR1C3 (0.72) | AKR1C3HDAC8ERCC5FEN1TNKS | |
| M-Phenoxybenzoic Acid For Cis-Isomer SCHEMBL29522837 | 0.78 | AKR1C3 (1.00) | AKR1C3HDAC8ERCC5FEN1TNKS | |
| SCHEMBL21887184 | 0.78 | AKR1C3 (0.78) | AKR1C3HDAC8ERCC5FEN1TNKS | |
| M-Phenoxybenzoic Acid For Cis-Isomer SCHEMBL30445868 | 0.78 | AKR1C3 (1.00) | AKR1C3HDAC8ERCC5FEN1TNKS | |
| SCHEMBL8897485 | 0.78 | AKR1C3 (0.78) | AKR1C3HDAC8ERCC5FEN1TNKS | |
| M-Phenoxybenzoic Acid For Cis-Isomer SCHEMBL128732 | 0.78 | AKR1C3 (1.00) | AKR1C3HDAC8ERCC5FEN1TNKS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1077957-A1 | OXYIMINOALKANOIC ACID DERIVATIVES WITH HYPOGLYCEMIC AND HYPOLIPIDEMIC ACTIVITY | Takeda Chemical Industries, Ltd. (JP) | 2001-02-28 | — | — | EP | disclosed |
| WO-1999058510-A1 | OXYIMINOALKANOIC ACID DERIVATIVES WITH HYPOGLYCEMIC AND HYPOLIPIDEMIC ACTIVITY | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1999-11-18 | — | — | WO | disclosed |