SCHEMBL78375

SCHEMBL78375

Clc1cccc(I)c1Cl

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30082341 1.00
SCHEMBL29227285 0.84
SCHEMBL3991309 0.77 TSHR (0.61)
SCHEMBL23239 0.77
SCHEMBL10664478 0.77
SCHEMBL109605 0.75
SCHEMBL30372108 0.75
SCHEMBL733271 0.74 TSHR (0.71)
Phosphine SCHEMBL22230521 0.74 TSHR (0.58)
Hydrochloric Acid SCHEMBL31618288 0.74 TSHR (0.58)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 872 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122080274-A Preparation method of functionalized polyolefin 2026-05-26 CN claimed
CN-120004776-A Synthesis method of beta-acyloxy-gamma-selenosulfonamide compound 重庆大学 2025-05-16 CN claimed
CN-119613305-A Catechol group-containing epoxy resin toughness curing agent and preparation method thereof 哈尔滨工业大学 2025-03-14 CN claimed
CN-118994170-A Process for preparing 1' -cyanonucleosides 吉利德科学公司 2024-11-22 CN claimed
US-12110271-B2 Manufacturing method for 4-methoxypyrrole derivatives DAEWOONG PHARMACEUTICAL CO., LTD. (KR) 2024-10-08 US claimed
CN-118702743-A Sulfonamide modified N-heterocyclic carbene complex as well as synthetic method and application thereof 常州大学 2024-09-27 CN claimed
US-12012431-B2 Methods of preparing 1′-cyano nucleosides GILEAD SCIENCES, INC. (US) 2024-06-18 US claimed
CN-118026934-A N-azole-4-methylbenzenesulfonamide compound and preparation method and application thereof 安徽理工大学 2024-05-14 CN claimed
CN-117603275-A Preparation method of polyketone catalyst and application of polyketone catalyst in catalyzing polyketone synthesis 万华化学集团股份有限公司 2024-02-27 CN claimed
CN-116903619-A FGFR4 inhibitor and synthesis method of crystalline salt thereof 贝达药业股份有限公司 2023-10-20 CN claimed
EP-0002564-B1 DERIVATIVES OF 7-OXO-1-AZABICYCLO(3.2.0)-HEPT-2-ENE-2-CARBOXYLIC ACID, THEIR PREPARATION, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND INTERMEDIATES BEECHAM GROUP PLC (GB) 1984-06-20 EP claimed
US-4358607-A CHLORINATION, DEHYDROCHLORINATION, HYDROLYSIS AMERICAN CYANAMID CO. (US) 1982-11-09 US claimed
EP-0005523-B1 D-HOMOSTEROIDS, PROCESS FOR THEIR PREPARATION F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) 1981-08-26 EP claimed
EP-0003863-B1 NOVEL ANDROSTADIENES, PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM Technobiotic Ltd. (CH) 1981-07-22 EP claimed
EP-0003863-A1 Novel androstadienes, processes for their preparation and pharmaceutical compositions containing them Technobiotic Ltd. (CH) 1979-09-05 EP claimed
EP-0002564-A1 Derivatives of 7-oxo-1-azabicyclo(3.2.0)-hept-2-ene-2-carboxylic acid, their preparation, pharmaceutical compositions containing them and intermediates BEECHAM GROUP PLC (GB) 1979-06-27 EP claimed
US-4158674-A Process for displacing nuclear iodine from substituted benzenes with chlorine THE DOW CHEMICAL COMPANY (US) 1979-06-19 US claimed
US-4100201-A Process for the preparation of halogenoacetals from esters RHONE-POULENC INDUSTRIES (FR) 1978-07-11 US claimed
US-4087465-A Process for the preparation of halogeno-acetals from enoxysilanes RHONE-POULENC INDUSTRIES (FR) 1978-05-02 US claimed
US-4061661-A Δ9(11) -5α-20-KETO STEROIDS AND PROCESS FOR THEIR PRODUCTION SCHERING AKTIENGESELLSCHAFT (DT) 1977-12-06 US claimed