Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.51 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | USP2 | O75604 | 2/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.50 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.50 |
| ▸ | TTPA | P49638 | 1/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.49 |
| ▸ | ALOX5 | P09917 | 5/20 | 0.48 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7825643 | 0.83 | MAPT (0.45) | CYP3A4TSHRPTGS1PTGS2CYP1A2 | |
| SCHEMBL18933886 | 0.82 | MAPT (0.55) | CYP3A4TSHRPTGS1PTGS2CYP1A2 | |
| SCHEMBL7834104 | 0.81 | MAPT (0.43) | CYP3A4TSHRPTGS1PTGS2CYP1A2 | |
| SCHEMBL7833222 | 0.81 | MAPT (0.43) | CYP3A4TSHRPTGS1PTGS2CYP1A2 | |
| SCHEMBL7826448 | 0.81 | MAPT (0.43) | CYP3A4TSHRPTGS1PTGS2CYP1A2 | |
| SCHEMBL7489357 | 0.79 | CYP3A4 (0.60) | CYP3A4TSHRPTGS1PTGS2CYP1A2 | |
| SCHEMBL22512463 | 0.78 | PTGS1 (0.60) | CYP3A4TSHRPTGS1PTGS2CYP1A2 | |
| SCHEMBL23692465 | 0.78 | MAPT (0.59) | CYP3A4TSHRPTGS1PTGS2CYP1A2 | |
| SCHEMBL7057443 | 0.78 | MAPT (0.59) | CYP3A4TSHRPTGS1PTGS2CYP1A2 | |
| SCHEMBL5672022 | 0.78 | NR1I2 (0.61) | CYP3A4TSHRPTGS1PTGS2CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0844245-B1 | Benzopyran derivatives, process for their preparation and pharmaceutical compositions containing them | ADIR (FR) | 2001-05-09 | — | — | EP | disclosed |
| US-5889045-A | ANTIDIABETIC AGENTS | ADIR ET COMPAGNIE (FR) | 1999-03-30 | — | — | US | disclosed |
| EP-0844245-A1 | Benzopyran derivatives, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1998-05-27 | — | — | EP | disclosed |