Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 5/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.47 |
| ▸ | APP | P05067 | 5/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.46 |
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CNR1 | P21554 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5516525 | 0.95 | APP (0.51) | NPSR1MEN1KMT2AAPPMAPT | |
| SCHEMBL7840330 | 0.83 | MAPT (0.42) | NPSR1MEN1KMT2AAPPMAPT | |
| SCHEMBL10293539 | 0.83 | FFAR1 (0.59) | NPSR1MEN1KMT2AMAPTALOX12 | |
| SCHEMBL13165361 | 0.81 | FFAR1 (0.46) | NPSR1MEN1KMT2AMAPTALOX12 | |
| SCHEMBL791494 | 0.79 | MEN1 (0.50) | NPSR1MEN1KMT2AMAPTALOX12 | |
| SCHEMBL10138010 | 0.77 | CYP11B1 (0.47) | MEN1KMT2AAPPMAPTKDM4E | |
| SCHEMBL5521150 | 0.77 | MEN1 (0.51) | NPSR1MEN1KMT2AMAPTALOX12 | |
| SCHEMBL6700683 | 0.76 | MAPT (0.46) | NPSR1MEN1KMT2AMAPTALOX12 | |
| SCHEMBL27553691 | 0.75 | FFAR1 (0.43) | NPSR1MEN1KMT2AMAPTALOX12 | |
| SCHEMBL5510993 | 0.74 | MEN1 (0.48) | NPSR1MEN1KMT2AMAPTALOX12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1162196-A1 | FUSED-RING COMPOUNDS AND USE THEREOF AS DRUGS | JAPAN TOBACCO INC. (JP) | 2001-12-12 | — | — | EP | disclosed |