Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 | P35367 | 4/20 | 0.53 |
| ▸ | TACR2 | P21452 | 3/20 | 0.53 |
| ▸ | TACR1 | P25103 | 3/20 | 0.53 |
| ▸ | TACR3 | P29371 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7844486 | 0.94 | TACR2 (0.62) | HRH1TACR2TACR1TACR3 | |
| SCHEMBL7846070 | 0.93 | TACR2 (0.51) | HRH1TACR2TACR1TACR3 | |
| SCHEMBL7838203 | 0.92 | TACR2 (0.58) | HRH1TACR2TACR1TACR3 | |
| SCHEMBL7842751 | 0.89 | TACR2 (0.46) | HRH1TACR2TACR1TACR3 | |
| SCHEMBL7839377 | 0.88 | TACR2 (0.56) | HRH1TACR2TACR1TACR3 | |
| SCHEMBL7845638 | 0.87 | TACR2 (0.61) | HRH1TACR2TACR1TACR3 | |
| SCHEMBL7839054 | 0.86 | TACR2 (0.56) | HRH1TACR2TACR1TACR3 | |
| SCHEMBL7842764 | 0.86 | TACR2 (0.58) | HRH1TACR2TACR1TACR3 | |
| SCHEMBL7839906 | 0.86 | TACR2 (0.57) | HRH1TACR2TACR1TACR3 | |
| SCHEMBL7842200 | 0.86 | TACR2 (0.54) | HRH1TACR2TACR1TACR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0946545-B1 | NOVEL CARBOXY SUBSTITUTED CYCLIC CARBOXAMIDE DERIVATIVES | AVENTIS PHARMA INC (US) | 2001-09-05 | — | — | EP | disclosed |
| US-5977139-A | Carboxysubstituted cyclic carboxamide derivatives | HOECHST MARION ROUSSEL, INC. (US) | 1999-11-02 | — | — | US | disclosed |
| EP-0946545-A1 | NOVEL CARBOXY SUBSTITUTED CYCLIC CARBOXAMIDE DERIVATIVES | HOECHST MARION ROUSSEL, INC. (US) | 1999-10-06 | — | — | EP | disclosed |
| WO-1998027085-A1 | NOVEL CARBOXY SUBSTITUTED CYCLIC CARBOXAMIDE DERIVATIVES | HOECHST MARION ROUSSEL, INC. (US) | 1998-06-25 | — | — | WO | disclosed |