Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7839419 | 0.94 | EDNRB (0.67) | EDNRBEDNRA | |
| SCHEMBL6313356 | 0.93 | EDNRB (0.77) | EDNRBEDNRA | |
| SCHEMBL7842527 | 0.93 | EDNRB (0.66) | EDNRBEDNRA | |
| SCHEMBL7841483 | 0.92 | EDNRB (0.66) | EDNRBEDNRA | |
| SCHEMBL6312773 | 0.91 | EDNRB (0.77) | EDNRBEDNRA | |
| SCHEMBL7842008 | 0.91 | EDNRB (0.64) | EDNRBEDNRA | |
| SCHEMBL7841833 | 0.91 | EDNRB (0.67) | EDNRBEDNRA | |
| SCHEMBL7843248 | 0.91 | EDNRB (0.63) | EDNRBEDNRA | |
| SCHEMBL7832475 | 0.90 | EDNRB (0.62) | EDNRBEDNRA | |
| SCHEMBL7831709 | 0.89 | EDNRB (0.71) | EDNRBEDNRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0882030-B1 | 2,1,3-BENZOTHIA(OXA)DIAZOLE DERIVATIVES HAVING AN ENDOTHELIN RECEPTOR ANTAGONISTIC EFFECT | MERCK PATENT GMBH (DE) | 2001-09-12 | — | — | EP | disclosed |
| US-6017939-A | 2,1,3-benzothia(OXA)diazole derivatives having an endothelin receptor antagonistic effect | MERCK PATENT GESELLSCHAFT (DE) | 2000-01-25 | — | — | US | disclosed |