Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1B1 | Q16678 | 6/20 | 0.57 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.57 |
| ▸ | CYP1A1 | P04798 | 3/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.53 |
| ▸ | GLA | P06280 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | BCHE | P06276 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7851301 | 0.84 | CYP1B1 (0.71) | CYP1B1ABCG2CYP1A1CYP1A2CYP2C19 | |
| SCHEMBL11405387 | 0.83 | ABCG2 (0.69) | CYP1B1ABCG2CYP1A1CYP1A2CYP2C19 | |
| SCHEMBL973106 | 0.83 | ABCG2 (0.69) | CYP1B1ABCG2CYP1A1CYP1A2CYP2C19 | |
| SCHEMBL31401681 | 0.79 | MEN1 (0.70) | CYP1A2CYP2C19KDM4EMEN1ALDH1A1 | |
| SCHEMBL30354048 | 0.79 | MEN1 (0.70) | CYP1A2CYP2C19KDM4EMEN1ALDH1A1 | |
| SCHEMBL28652 | 0.79 | MEN1 (0.70) | CYP1A2CYP2C19KDM4EMEN1ALDH1A1 | |
| SCHEMBL7841355 | 0.78 | MAPT (0.54) | CYP1B1ABCG2CYP1A1CYP1A2CYP2C19 | |
| Calcium SCHEMBL31214892 | 0.77 | MEN1 (0.68) | CYP1A2CYP2C19KDM4EMEN1ALDH1A1 | |
| SCHEMBL10417205 | 0.77 | MEN1 (0.68) | CYP1A2CYP2C19KDM4EMEN1ALDH1A1 | |
| Magnesium SCHEMBL31214938 | 0.77 | MEN1 (0.68) | CYP1A2CYP2C19KDM4EMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20010012905-A1 | Synthesis of pyrazolinylnaphthalic acid derivatives | EMAGIN CORPORATION | 2001-08-09 | — | — | US | claimed |
| US-6288232-B2 | REACTION OF ACETYLNAPHTHALIC ANHYDRIDE AND ALDEHYDE IN THE PRESENCE OF AQUEOUS BASE AND BOILING IN THE PRESENCE OF ANILINE COMPOUND | EMAGIN CORPORATION | 2001-09-11 | — | — | US | disclosed |
| US-20010012905-A1 | Synthesis of pyrazolinylnaphthalic acid derivatives | EMAGIN CORPORATION | 2001-08-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010012905-A1 | Synthesis of pyrazolinylnaphthalic acid derivatives | AHR, NAT1, ARSA | CYP1B1 39/4885ABCG2 342/4885CYP1A1 9/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.