Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EDNRA | P25101 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7840466 | 1.00 | EDNRA (0.52) | EDNRA | |
| SCHEMBL7842151 | 0.97 | EDNRA (0.49) | EDNRA | |
| SCHEMBL7842154 | 0.97 | EDNRA (0.49) | EDNRA | |
| SCHEMBL7841285 | 0.95 | EDNRA (0.50) | EDNRA | |
| SCHEMBL7844641 | 0.95 | EDNRA (0.50) | EDNRA | |
| SCHEMBL7842567 | 0.93 | EDNRA (0.63) | EDNRA | |
| SCHEMBL7840804 | 0.93 | EDNRA (0.63) | EDNRA | |
| SCHEMBL7844850 | 0.93 | NPC1 (0.48) | EDNRA | |
| SCHEMBL7843075 | 0.93 | MEN1 (0.48) | EDNRA | |
| SCHEMBL7842560 | 0.93 | EDNRA (0.63) | EDNRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0882030-B1 | 2,1,3-BENZOTHIA(OXA)DIAZOLE DERIVATIVES HAVING AN ENDOTHELIN RECEPTOR ANTAGONISTIC EFFECT | MERCK PATENT GMBH (DE) | 2001-09-12 | — | — | EP | disclosed |