Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7831359 | 0.98 | EDNRA (0.66) | EDNRAEDNRB | |
| SCHEMBL7830311 | 0.97 | EDNRA (0.67) | EDNRAEDNRB | |
| SCHEMBL7840261 | 0.94 | EDNRB (0.62) | EDNRAEDNRB | |
| SCHEMBL7831927 | 0.94 | EDNRB (0.72) | EDNRAEDNRB | |
| SCHEMBL7841837 | 0.94 | EDNRB (0.62) | EDNRAEDNRB | |
| SCHEMBL7832086 | 0.94 | EDNRB (0.72) | EDNRAEDNRB | |
| SCHEMBL7840626 | 0.93 | EDNRA (0.60) | EDNRAEDNRB | |
| SCHEMBL7838601 | 0.92 | EDNRB (0.60) | EDNRAEDNRB | |
| SCHEMBL7840533 | 0.92 | EDNRA (0.62) | EDNRAEDNRB | |
| SCHEMBL7844633 | 0.92 | EDNRB (0.60) | EDNRAEDNRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0882030-B1 | 2,1,3-BENZOTHIA(OXA)DIAZOLE DERIVATIVES HAVING AN ENDOTHELIN RECEPTOR ANTAGONISTIC EFFECT | MERCK PATENT GMBH (DE) | 2001-09-12 | — | — | EP | disclosed |
| US-6017939-A | 2,1,3-benzothia(OXA)diazole derivatives having an endothelin receptor antagonistic effect | MERCK PATENT GESELLSCHAFT (DE) | 2000-01-25 | — | — | US | disclosed |
| EP-0882030-A1 | 2,1,3-BENZOTHIA(OXA)DIAZOLE DERIVATIVES HAVING AN ENDOTHELIN RECEPTOR ANTAGONISTIC EFFECT | MERCK PATENT GmbH (DE) | 1998-12-09 | — | — | EP | disclosed |
| WO-1998042702-A1 | ENDOTHELIN-RECEPTOR ANTAGONISTS | MERCK PATENT GMBH (DE) | 1998-10-01 | — | — | WO | disclosed |
| WO-1997030982-A1 | 2,1,3-BENZOTHIA(OXA)DIAZOLE DERIVATIVES HAVING AN ENDOTHELIN RECEPTOR ANTAGONISTIC EFFECT | MERCK Patent Gesellschaft mit beschränkter Haftung (DE) | 1997-08-28 | — | — | WO | disclosed |