Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 19/20 | 0.63 |
| ▸ | FNTB | P49356 | 17/20 | 0.63 |
| ▸ | PGGT1B | P53609 | 15/20 | 0.63 |
| ▸ | NRAS | P01111 | 1/20 | 0.47 |
| ▸ | HRAS | P01112 | 1/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7839004 | 0.99 | FNTA (0.62) | FNTAFNTBPGGT1BNRASHRAS | |
| SCHEMBL7839464 | 0.82 | FNTA (0.62) | FNTAFNTBPGGT1BNRASHRAS | |
| SCHEMBL7842924 | 0.81 | FNTA (0.60) | FNTAFNTBPGGT1BNRASHRAS | |
| Hydrochloric Acid SCHEMBL7844275 | 0.81 | FNTA (0.61) | FNTAFNTBPGGT1BNRASHRAS | |
| SCHEMBL7830749 | 0.81 | FNTA (0.67) | FNTAFNTBPGGT1BNRASHRAS | |
| Hydrochloric Acid SCHEMBL7843843 | 0.81 | FNTA (0.59) | FNTAFNTBPGGT1BNRASHRAS | |
| SCHEMBL7839218 | 0.80 | FNTA (0.65) | FNTAFNTBPGGT1BNRASHRAS | |
| SCHEMBL7842402 | 0.79 | FNTA (0.67) | FNTAFNTBPGGT1B | |
| Hydrochloric Acid SCHEMBL7843273 | 0.79 | FNTA (0.65) | FNTAFNTBPGGT1BNRASHRAS | |
| SCHEMBL31471990 | 0.78 | FNTA (0.77) | FNTAFNTBPGGT1BNRASHRAS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1087770-A4 | INHIBITORS OF PRENYL-PROTEIN TRANSFERASE | MERCK & CO INC (US) | 2001-11-14 | — | — | EP | claimed |
| EP-1087770-A1 | INHIBITORS OF PRENYL-PROTEIN TRANSFERASE | Merck & Co., Inc. (US) | 2001-04-04 | — | — | EP | claimed |
| WO-1999065494-A1 | INHIBITORS OF PRENYL-PROTEIN TRANSFERASE | MERCK & CO., INC. (US) | 1999-12-23 | — | — | WO | claimed |
| EP-1087770-A4 | INHIBITORS OF PRENYL-PROTEIN TRANSFERASE | MERCK & CO INC (US) | 2001-11-14 | — | — | EP | disclosed |
| EP-1087770-A1 | INHIBITORS OF PRENYL-PROTEIN TRANSFERASE | Merck & Co., Inc. (US) | 2001-04-04 | — | — | EP | disclosed |
| US-6172076-B1 | HETEROCYCLE-SUBSTITUTED 1,3,8-TRIAZASPIRO(4,5)DECANE DERIVATIVES; TREATING ARTERIOSCLEROSIS | MERCK & CO., INC. | 2001-01-09 | — | — | US | disclosed |
| WO-1999065494-A1 | INHIBITORS OF PRENYL-PROTEIN TRANSFERASE | MERCK & CO., INC. (US) | 1999-12-23 | — | — | WO | disclosed |