Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 6/20 | 0.51 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | TOP2A | P11388 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.34 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.34 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.32 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.32 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7848527 | 0.87 | KCNH2 (0.67) | KCNH2HRH3ALDH1A1KDM4ELMNA | |
| SCHEMBL7841158 | 0.87 | KCNH2 (0.67) | KCNH2HRH3ALDH1A1KDM4ELMNA | |
| SCHEMBL7848524 | 0.87 | KCNH2 (0.67) | KCNH2HRH3ALDH1A1KDM4ELMNA | |
| Hydrochloric Acid SCHEMBL10443267 | 0.87 | KCNH2 (0.54) | KCNH2HRH3ALDH1A1KDM4ELMNA | |
| Hydrochloric Acid SCHEMBL10443393 | 0.87 | KCNH2 (0.54) | KCNH2HRH3ALDH1A1KDM4ELMNA | |
| SCHEMBL7848651 | 0.85 | KCNH2 (0.41) | KCNH2HRH3ALDH1A1KDM4EHPGD | |
| SCHEMBL7850124 | 0.84 | KDM4E (0.49) | HRH3ALDH1A1KDM4ELMNAHPGD | |
| SCHEMBL7852291 | 0.84 | POLB (0.43) | KCNH2HRH3ALDH1A1KDM4ELMNA | |
| SCHEMBL9048539 | 0.81 | HRH3 (0.53) | KCNH2HRH3ALDH1A1KDM4ELMNA | |
| SCHEMBL1858180 | 0.81 | KCNH2 (0.76) | KCNH2HRH3ALDH1A1KDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0677050-B1 | NOVEL PYRIDONE CARBOXYLIC ACID DERIVATIVES | CHEIL JEDANG CORP (KR) | 2001-08-16 | — | — | EP | claimed |