Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHA2 | P29317 | 1/20 | 0.56 |
| ▸ | FLT4 | P35916 | 1/20 | 0.56 |
| ▸ | GSK3B | P49841 | 1/20 | 0.56 |
| ▸ | RARB | P10826 | 1/20 | 0.56 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.56 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 5/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | XBP1 | P17861 | 1/20 | 0.54 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.54 |
| ▸ | RELA | Q04206 | 1/20 | 0.54 |
| ▸ | DPP4 | P27487 | 6/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9067359 | 1.00 | EPHA2 (0.56) | EPHA2FLT4GSK3BRARBTBXAS1 | |
| SCHEMBL9066234 | 0.91 | EPHA2 (0.69) | EPHA2FLT4GSK3BRARBTBXAS1 | |
| SCHEMBL7849133 | 0.90 | EPHA2 (0.45) | EPHA2FLT4GSK3BRARBTBXAS1 | |
| SCHEMBL9066532 | 0.85 | DPP4 (0.61) | EPHA2FLT4GSK3BRARBTBXAS1 | |
| SCHEMBL9066828 | 0.85 | DPP4 (0.61) | EPHA2FLT4GSK3BRARBTBXAS1 | |
| SCHEMBL7851369 | 0.84 | EPHA2 (0.56) | EPHA2FLT4GSK3BRARBTBXAS1 | |
| SCHEMBL7851370 | 0.84 | EPHA2 (0.56) | EPHA2FLT4GSK3BRARBTBXAS1 | |
| SCHEMBL7851214 | 0.84 | EPHA2 (0.56) | EPHA2FLT4GSK3BRARBTBXAS1 | |
| SCHEMBL9148377 | 0.83 | EPHA2 (0.57) | EPHA2FLT4GSK3BRARBTBXAS1 | |
| SCHEMBL27678675 | 0.80 | KMT2A (0.82) | EPHA2FLT4GSK3BRARBTBXAS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0677050-B1 | NOVEL PYRIDONE CARBOXYLIC ACID DERIVATIVES | CHEIL JEDANG CORP (KR) | 2001-08-16 | — | — | EP | claimed |
| EP-0677050-B1 | NOVEL PYRIDONE CARBOXYLIC ACID DERIVATIVES | CHEIL JEDANG CORP (KR) | 2001-08-16 | — | — | EP | disclosed |
| US-5527910-A | BACTERICIDES; STAPHYLOCOCCUS, STREPTOCOCCUS INFECTIONS | CHEIL FOODS & CHEMICALS, INC. (KR) | 1996-06-18 | — | — | US | disclosed |
| WO-1996006090-A1 | RING D-MODIFIED GIBBERELLIN COMPOUNDS, AND PREPARATION AND USE THEREOF | THE AUSTRALIAN NATIONAL UNIVERSITY (AU) | 1996-02-29 | — | — | WO | disclosed |