Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
| ▸ | CNR2 | P34972 | 11/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 6/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.41 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 5/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6766761 | 0.86 | MAPK1 (0.45) | MAPK1RXFP1CNR2CYP2C9CYP1A2 | |
| SCHEMBL6716698 | 0.84 | EGLN1 (0.47) | MAPK1RXFP1EGLN1 | |
| SCHEMBL6670932 | 0.84 | MAPK1 (0.41) | MAPK1EGLN1 | |
| SCHEMBL6713866 | 0.83 | EGLN1 (0.46) | MAPK1RXFP1CNR2CYP2C9CYP1A2 | |
| SCHEMBL6201283 | 0.83 | KCNH2 (0.54) | RXFP1 | |
| SCHEMBL6198849 | 0.82 | EGLN1 (0.51) | RXFP1CNR2CYP2C9CYP1A2CYP3A4 | |
| SCHEMBL6699267 | 0.82 | MAPK1 (0.42) | MAPK1RXFP1CNR2CYP2C9CYP1A2 | |
| SCHEMBL6200824 | 0.82 | EGLN1 (0.48) | CYP2C9CYP1A2CYP3A4EGLN1CYP2C19 | |
| SCHEMBL6669425 | 0.81 | MAPK1 (0.45) | MAPK1RXFP1EGLN1 | |
| SCHEMBL6194761 | 0.81 | POLA1 (0.54) | CNR2CYP2C9CYP1A2CYP3A4EGLN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140850-A1 | QUINOLINECARBOXAMIDES AS ANTIVIRAL AGENTS | PHARMACIA & UPJOHN COMPANY (US) | 2001-10-10 | — | — | EP | disclosed |
| US-6248739-B1 | DNA POLYMERASE INHIBITORS EFFECTIVE AGAINST HERPESVIRUSES | PHARMACIA & UPJOHN COMPANY | 2001-06-19 | — | — | US | disclosed |
| WO-2000040561-A1 | QUINOLINECARBOXAMIDES AS ANTIVIRAL AGENTS | PHARMACIA & UPJOHN COMPANY (US) | 2000-07-13 | — | — | WO | disclosed |