Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CALML3 | P27482 | 5/20 | 0.44 |
| ▸ | MAOA | P21397 | 9/20 | 0.40 |
| ▸ | MAOB | P27338 | 5/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | SDHA | P31040 | 1/20 | 0.40 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.39 |
| ▸ | RORC | P51449 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.38 |
| ▸ | SCD | O00767 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7852375 | 1.00 | CALML3 (0.44) | CALML3MAOAMAOBLMNAPTGS1 | |
| SCHEMBL7096187 | 1.00 | CALML3 (0.44) | CALML3MAOAMAOBLMNAPTGS1 | |
| SCHEMBL7084600 | 0.88 | CALML3 (0.44) | CALML3MAOAMAOBLMNAPTGS1 | |
| SCHEMBL7084601 | 0.88 | CALML3 (0.44) | CALML3MAOAMAOBLMNAPTGS1 | |
| SCHEMBL7853448 | 0.86 | CALML3 (0.43) | CALML3MAOAMAOBLMNAPTGS1 | |
| SCHEMBL7853449 | 0.86 | CALML3 (0.43) | CALML3MAOAMAOBLMNAPTGS1 | |
| SCHEMBL5834842 | 0.84 | CALML3 (0.59) | CALML3MAOAMAOBLMNAPTGS1 | |
| SCHEMBL5231089 | 0.84 | CALML3 (0.59) | CALML3MAOAMAOBLMNAPTGS1 | |
| SCHEMBL5232610 | 0.84 | PTGDR2 (0.51) | PTGDR2ROCK2SCD | |
| SCHEMBL7078516 | 0.84 | CALML3 (0.59) | CALML3MAOAMAOBLMNAPTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1121358-A1 | HETEROCYCLYLAMINOMETHYLOXAZOLIDINONES AS ANTIBACTERIALS | AstraZeneca AB (SE) | 2001-08-08 | — | — | EP | disclosed |
| WO-2000021960-A1 | HETEROCYCLYL AMINO METHYLOXA ZOLIDINONES AS ANTIBACTERIALS | ASTRAZENECA AB (SE) | 2000-04-20 | — | — | WO | disclosed |