⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4153983 | 0.72 | — | — | |
| SCHEMBL5756681 | 0.69 | — | — | |
| SCHEMBL30239899 | 0.68 | — | — | |
| SCHEMBL15962191 | 0.68 | — | — | |
| SCHEMBL5139987 | 0.68 | — | — | |
| SCHEMBL7844155 | 0.66 | — | — | |
| SCHEMBL8912720 | 0.65 | UHRF1 (0.32) | — | |
| SCHEMBL24925066 | 0.64 | — | — | |
| SCHEMBL28430279 | 0.64 | PIK3CD (0.34) | — | |
| SCHEMBL13787656 | 0.64 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0399731-B2 | Azaindenes | ASTRAZENECA AB (SE) | 2001-07-11 | — | — | EP | disclosed |
| EP-0399731-B1 | Azaindenes | ZENECA LTD (GB) | 1993-12-08 | — | — | EP | disclosed |
| EP-0399731-A1 | Azaindenes | ZENECA LIMITED (GB) | 1990-11-28 | — | — | EP | disclosed |