Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | DHODH | Q02127 | 3/20 | 0.34 |
| ▸ | GAA | P10253 | 4/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | NPY1R | P25929 | 1/20 | 0.33 |
| ▸ | NPY2R | P49146 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | JAK1 | P23458 | 2/20 | 0.33 |
| ▸ | JAK3 | P52333 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8694662 | 1.00 | NPSR1 (0.42) | NPSR1MAPTCYP2D6CYP3A4CYP1A2 | |
| SCHEMBL7850181 | 0.86 | NPSR1 (0.45) | NPSR1MAPTCYP2D6CYP3A4CYP1A2 | |
| SCHEMBL7849686 | 0.86 | NPSR1 (0.40) | NPSR1MAPTCYP2D6CYP3A4CYP1A2 | |
| SCHEMBL7956810 | 0.81 | CYP2C19 (0.49) | NPSR1MAPTCYP2D6CYP3A4CYP1A2 | |
| SCHEMBL7956814 | 0.81 | CYP2C19 (0.49) | NPSR1MAPTCYP2D6CYP3A4CYP1A2 | |
| SCHEMBL8695480 | 0.81 | NPSR1 (0.43) | NPSR1MAPTCYP2D6CYP3A4CYP1A2 | |
| SCHEMBL9145758 | 0.80 | NPSR1 (0.40) | NPSR1MAPTCYP2D6CYP3A4CYP1A2 | |
| SCHEMBL10774716 | 0.80 | POLB (0.39) | NPSR1MAPTCYP1A2CYP2C19DHODH | |
| SCHEMBL7850451 | 0.80 | NPSR1 (0.35) | NPSR1MAPTCYP2D6CYP3A4CYP1A2 | |
| SCHEMBL7841807 | 0.80 | NPSR1 (0.42) | NPSR1MAPTCYP2D6CYP3A4CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0726270-B1 | Derivatives of 1,6-naphthyridone carboxylic acids | BAYER AG (DE) | 2001-05-23 | — | — | EP | disclosed |
| US-5811433-A | ANTIMICROBIALS | BAYER AKTIENGESELLSCHAFT (DE) | 1998-09-22 | — | — | US | disclosed |
| EP-0726270-A1 | Derivatives of 1,6-naphthyridine carboxylic acids | BAYER AG (DE) | 1996-08-14 | — | — | EP | disclosed |