Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 3/20 | 0.53 |
| ▸ | CYP4A11 | Q02928 | 3/20 | 0.53 |
| ▸ | LPL | P06858 | 2/20 | 0.47 |
| ▸ | LIPG | Q9Y5X9 | 2/20 | 0.47 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.47 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.47 |
| ▸ | PPARG | P37231 | 2/20 | 0.47 |
| ▸ | PPARA | Q07869 | 2/20 | 0.47 |
| ▸ | MAP1LC3B | Q9GZQ8 | 1/20 | 0.45 |
| ▸ | MAP1LC3A | Q9H492 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | RARB | P10826 | 1/20 | 0.45 |
| ▸ | PLK1 | P53350 | 1/20 | 0.45 |
| ▸ | XIAP | P98170 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11757933 | 0.87 | CYP4F2 (0.54) | CYP4F2CYP4A11LPLLIPGSPHK2 | |
| SCHEMBL8341269 | 0.86 | CYP4F2 (0.53) | CYP4F2CYP4A11LPLLIPGSPHK2 | |
| SCHEMBL3387825 | 0.86 | FOLH1 (0.58) | CYP4F2CYP4A11PPARGPPARASMN1; SMN2 | |
| SCHEMBL8098007 | 0.86 | CYP4F2 (0.53) | CYP4F2CYP4A11LPLLIPGSPHK2 | |
| SCHEMBL31124111 | 0.86 | FOLH1 (0.58) | CYP4F2CYP4A11PPARGPPARASMN1; SMN2 | |
| SCHEMBL5194300 | 0.84 | CYP4F2 (0.51) | CYP4F2CYP4A11LPLLIPGSPHK2 | |
| SCHEMBL5194309 | 0.84 | SPHK2 (0.52) | CYP4F2CYP4A11LPLLIPGSPHK2 | |
| SCHEMBL12221840 | 0.84 | CYP4F2 (0.51) | CYP4F2CYP4A11LPLLIPGSPHK2 | |
| SCHEMBL8087128 | 0.84 | CYP4F2 (0.51) | CYP4F2CYP4A11LPLLIPGSPHK2 | |
| SCHEMBL19466330 | 0.84 | CYP4F2 (0.53) | CYP4F2CYP4A11LPLLIPGSPHK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105142875-B | The method for preparing the photochromic dichroism film with the optical distortion for reducing | 光学转变公司 | 2017-07-07 | — | — | CN | disclosed |
| CN-103635837-B | Polarization photochromic article | 光学转变公司 | 2016-08-17 | — | — | CN | disclosed |
| EP-0454501-B1 | Benzylidenethiazolidine derivatives, their preparation and their use for the inhibition of lipid peroxides | SANKYO CO (JP) | 2001-09-05 | — | — | EP | disclosed |
| EP-0839812-A1 | Preparation of benzylthiazolidine derivatives | Sankyo Company Limited (JP) | 1998-05-06 | — | — | EP | disclosed |
| US-5387596-A | Treating arteriosclerosis | SANKYO COMPANY, LIMITED (JP) | 1995-02-07 | — | — | US | disclosed |
| EP-0454501-A2 | Benzylidenethiazolidine derivatives, their preparation and their use for the inhibition of lipid peroxides | Sankyo Company Limited (JP) | 1991-10-30 | — | — | EP | disclosed |