Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | KDM1A | O60341 | 1/20 | 0.37 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.36 |
| ▸ | AKT1 | P31749 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25064706 | 0.85 | DEGS1 (0.36) | KDM1ADEGS1AKT1SMN1; SMN2MEN1 | |
| SCHEMBL18173271 | 0.76 | AKT1 (0.43) | KDM1ADEGS1AKT1SMN1; SMN2MEN1 | |
| SCHEMBL1136742 | 0.76 | AKT1 (0.43) | KDM1ADEGS1AKT1SMN1; SMN2MEN1 | |
| SCHEMBL3689955 | 0.76 | AKT1 (0.43) | KDM1ADEGS1AKT1SMN1; SMN2MEN1 | |
| SCHEMBL25467855 | 0.75 | DEGS1 (0.39) | KDM1ADEGS1AKT1SMN1; SMN2MEN1 | |
| SCHEMBL27478247 | 0.74 | AKT1 (0.41) | KDM1ADEGS1AKT1SMN1; SMN2MEN1 | |
| SCHEMBL24922546 | 0.74 | DEGS1 (0.38) | KDM1ADEGS1AKT1SMN1; SMN2MEN1 | |
| SCHEMBL24030217 | 0.70 | — | — | |
| SCHEMBL26198838 | 0.69 | KDM1A (0.42) | HDAC1HDAC2KDM1ALMNA | |
| SCHEMBL22252510 | 0.68 | DEGS1 (0.44) | KDM1ADEGS1AKT1SMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010151689-A1 | HETEROCYCLIC COMPOUNDS FOR THE TREATMENT OF NEUROLOGICAL AND PSYCHOLOGICAL DISORDERS | ALKERMES, INC. (US) | 2010-12-29 | — | — | WO | disclosed |