Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY2 | P41231 | 19/20 | 0.88 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7844224 | 0.94 | P2RY2 (1.00) | P2RY2 | |
| SCHEMBL7840348 | 0.93 | P2RY2 (0.91) | P2RY2 | |
| SCHEMBL7841848 | 0.92 | P2RY2 (0.73) | P2RY2NPC1ALDH1A1POLBRAB9A | |
| SCHEMBL7841362 | 0.91 | P2RY2 (0.73) | P2RY2 | |
| SCHEMBL7839810 | 0.90 | P2RY2 (0.91) | P2RY2NPC1RAB9A | |
| SCHEMBL7841381 | 0.87 | P2RY2 (0.85) | P2RY2NPC1RAB9A | |
| SCHEMBL7832746 | 0.86 | P2RY2 (0.82) | P2RY2ALDH1A1 | |
| SCHEMBL7838490 | 0.85 | P2RY2 (1.00) | P2RY2 | |
| SCHEMBL7840113 | 0.85 | P2RY2 (0.82) | P2RY2SMN1; SMN2 | |
| SCHEMBL7840419 | 0.84 | P2RY2 (0.76) | P2RY2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0984963-B1 | NOVEL COMPOUNDS | ASTRAZENECA AB (SE) | 2001-04-11 | — | — | EP | claimed |
| US-6162808-A | Compounds | ASTRAZENECA U.K. LIMITED (GB) | 2000-12-19 | — | — | US | claimed |
| EP-0984963-B1 | NOVEL COMPOUNDS | ASTRAZENECA AB (SE) | 2001-04-11 | — | — | EP | disclosed |
| US-6162808-A | Compounds | ASTRAZENECA U.K. LIMITED (GB) | 2000-12-19 | — | — | US | disclosed |