Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | CRHBP | P24387 | 2/20 | 0.41 |
| ▸ | CRHR2 | Q13324 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | SIRT2 | Q8IXJ6 | 3/20 | 0.39 |
| ▸ | SIRT1 | Q96EB6 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4785677 | 0.85 | SMN1; SMN2 (0.53) | SMN1; SMN2GAANISCHLMNACRHBP | |
| SCHEMBL5279172 | 0.84 | SMN1; SMN2 (0.44) | SMN1; SMN2GAANPC1RAB9ANISCH | |
| SCHEMBL1134762 | 0.82 | SMN1; SMN2 (0.53) | SMN1; SMN2GAANPC1RAB9ALMNA | |
| SCHEMBL4452603 | 0.82 | SMN1; SMN2 (0.53) | SMN1; SMN2GAANPC1RAB9ALMNA | |
| SCHEMBL30946854 | 0.73 | NISCH (0.71) | SMN1; SMN2NPC1RAB9ANISCHHTT | |
| SCHEMBL2977327 | 0.73 | NISCH (0.71) | SMN1; SMN2NPC1RAB9ANISCHHTT | |
| SCHEMBL8487833 | 0.72 | SMN1; SMN2 (0.59) | SMN1; SMN2GAANPC1RAB9ALMNA | |
| SCHEMBL11788057 | 0.72 | SMN1; SMN2 (0.59) | SMN1; SMN2GAANPC1RAB9ALMNA | |
| Hydrochloric Acid SCHEMBL11099585 | 0.71 | NISCH (0.69) | SMN1; SMN2NPC1RAB9ANISCHHTT | |
| Hydrochloric Acid SCHEMBL17845907 | 0.71 | NISCH (0.69) | SMN1; SMN2NPC1RAB9ANISCHHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1150565-A1 | THIAZOLE DERIVATIVES AND COMBINATORIAL LIBRARIES THEREOF | LION bioscience AG (DE) | 2001-11-07 | — | — | EP | claimed |
| WO-2000045635-A1 | THIAZOLE DERIVATIVES AND COMBINATORIAL LIBRARIES THEREOF | LION BIOSCIENCE AG (DE) | 2000-08-10 | — | — | WO | claimed |
| EP-1150565-A1 | THIAZOLE DERIVATIVES AND COMBINATORIAL LIBRARIES THEREOF | LION bioscience AG (DE) | 2001-11-07 | — | — | EP | disclosed |
| WO-2000045635-A1 | THIAZOLE DERIVATIVES AND COMBINATORIAL LIBRARIES THEREOF | LION BIOSCIENCE AG (DE) | 2000-08-10 | — | — | WO | disclosed |