SCHEMBL7843219

SCHEMBL7843219

CCCCCCCCCCCC=NCCO

nearest known ligand 0.44

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.44
LMNA P02545 2/20 0.44
MEN1 O00255 2/20 0.44
KMT2A Q03164 2/20 0.44
ALDH1A1 P00352 2/20 0.44
HSD17B10 Q99714 1/20 0.44
SMN1; SMN2 Q16637 1/20 0.40
THRB P10828 1/20 0.39
HTT P42858 1/20 0.39
MAPT P10636 1/20 0.39
EP300 Q09472 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27987518 1.00 TSHR (0.44) TSHRLMNAMEN1KMT2AALDH1A1
SCHEMBL27987090 1.00 TSHR (0.44) TSHRLMNAMEN1KMT2AALDH1A1
SCHEMBL16378586 1.00 TSHR (0.44) TSHRLMNAMEN1KMT2AALDH1A1
SCHEMBL18683556 0.87 SMN1; SMN2 (0.46) TSHRLMNAMEN1KMT2AALDH1A1
SCHEMBL24864672 0.84 TSHR (0.44) TSHRMEN1KMT2ATHRBEP300
SCHEMBL417789 0.84 TSHR (0.44) TSHRMEN1KMT2ATHRBEP300
SCHEMBL11760325 0.84 TSHR (0.44) TSHRMEN1KMT2ATHRBEP300
SCHEMBL11760319 0.84 TSHR (0.44) TSHRMEN1KMT2ATHRBEP300
SCHEMBL21581093 0.84 TSHR (0.44) TSHRMEN1KMT2ATHRBEP300
SCHEMBL24183668 0.84 TSHR (0.44) TSHRMEN1KMT2ATHRBEP300

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104169403-A Lubricating oil composition and sliding mechanism using same IDEMITSU KOSAN CO 2014-11-26 CN disclosed
CN-104169402-A Lubricating oil composition and sliding mechanism using same IDEMITSU KOSAN CO 2014-11-26 CN disclosed
US-6171521-B1 Zwitterionic water-soluble substituted imine corrosion inhibitors NALCO/EXXON ENERGY CHEMICALS, L.P. 2001-01-09 US disclosed
US-5993693-A PREFERRED ZWITTERIONIC IMINES ARE THE REACTION PRODUCTS OF THE MICHAEL ADDITION OF ACRYLIC ACID TO AN IMINE. NALCO/EXXON ENERGY CHEMICALS, L.P. (US) 1999-11-30 US disclosed