Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F7 | P08709 | 17/20 | 0.62 |
| ▸ | F3 | P13726 | 16/20 | 0.62 |
| ▸ | F2 | P00734 | 16/20 | 0.62 |
| ▸ | F10 | P00742 | 16/20 | 0.62 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.62 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.62 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.62 |
| ▸ | PLG | P00747 | 9/20 | 0.56 |
| ▸ | PLAU | P00749 | 3/20 | 0.52 |
| ▸ | PLAT | P00750 | 2/20 | 0.52 |
| ▸ | KLK1 | P06870 | 1/20 | 0.49 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.49 |
| ▸ | F9 | P00740 | 1/20 | 0.47 |
| ▸ | F11 | P03951 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7657056 | 0.96 | F7 (0.58) | F7F3F2F10PRSS1 | |
| SCHEMBL7660372 | 0.96 | F7 (0.57) | F7F3F2F10PRSS1 | |
| SCHEMBL7655682 | 0.93 | F7 (0.54) | F7F3F2F10PRSS1 | |
| SCHEMBL7657064 | 0.88 | F10 (0.49) | F7F3F2F10PRSS1 | |
| SCHEMBL7657784 | 0.86 | F3 (0.72) | F7F3F2F10PRSS1 | |
| SCHEMBL7655686 | 0.86 | F2 (0.47) | F7F3F2F10PRSS1 | |
| SCHEMBL7654813 | 0.84 | F2 (0.66) | F7F3F2F10PRSS1 | |
| SCHEMBL7664920 | 0.83 | F3 (0.67) | F7F3F2F10PRSS1 | |
| SCHEMBL7661337 | 0.82 | F2 (0.69) | F7F3F2F10PRSS1 | |
| SCHEMBL7663228 | 0.82 | F2 (0.71) | F7F3F2F10PRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1078917-A1 | AMIDINO DERIVATIVES AND DRUGS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | ONO PHARMACEUTICAL CO., LTD. (JP) | 2001-02-28 | — | — | EP | claimed |