Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.32 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.32 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.31 |
| ▸ | MGLL | Q99685 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7843391 | 1.00 | TLR7 (0.32) | TLR7TRPA1TBXAS1MGLL | |
| Hydrochloric Acid SCHEMBL7847709 | 0.99 | TLR7 (0.32) | TLR7TRPA1TBXAS1MGLL | |
| Hydrochloric Acid SCHEMBL7847711 | 0.99 | TLR7 (0.32) | TLR7TRPA1TBXAS1MGLL | |
| SCHEMBL7847011 | 0.83 | HSD17B10 (0.34) | TRPA1 | |
| SCHEMBL7847008 | 0.83 | HSD17B10 (0.34) | TRPA1 | |
| Hydrochloric Acid SCHEMBL7847068 | 0.82 | HSD17B10 (0.34) | TRPA1 | |
| Hydrochloric Acid SCHEMBL7847072 | 0.82 | HSD17B10 (0.34) | TRPA1 | |
| SCHEMBL7846231 | 0.81 | SPHK2 (0.42) | TLR7TBXAS1 | |
| SCHEMBL7846233 | 0.81 | SPHK2 (0.42) | TLR7TBXAS1 | |
| Hydrochloric Acid SCHEMBL7843444 | 0.80 | SPHK2 (0.41) | TBXAS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0767790-B1 | CONDENSED IMIDAZOLE COMPOUNDS, THEIR PRODUCTION AND USE | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2001-12-12 | — | — | EP | disclosed |
| EP-0767790-A1 | CONDENSED IMIDAZOLE COMPOUNDS, THEIR PRODUCTION AND USE | Takeda Chemical Industries, Ltd. (JP) | 1997-04-16 | — | — | EP | disclosed |
| WO-1995035296-A1 | CONDENSED IMIDAZOLE COMPOUNDS, THEIR PRODUCTION AND USE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1995-12-28 | — | — | WO | disclosed |