⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL27874294 | 0.98 | — | — | |
| SCHEMBL3777009 | 0.82 | — | — | |
| SCHEMBL27918945 | 0.79 | — | — | |
| SCHEMBL17734086 | 0.78 | — | — | |
| SCHEMBL13021206 | 0.73 | — | — | |
| SCHEMBL27729359 | 0.71 | — | — | |
| Bromide SCHEMBL28337037 | 0.71 | — | — | |
| SCHEMBL7747951 | 0.71 | — | — | |
| SCHEMBL27537074 | 0.71 | — | — | |
| SCHEMBL9644704 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101781305-A | Method for artificially synthesizing galanthamine | TAIZHOU JINZHAO WEIYE FINE CHE | 2010-07-21 | — | — | CN | claimed |
| WO-2022208382-A1 | NOVEL DIALKOXYNAPHTHO[2,3-C]FURAN-1(3H)-ONE DERIVATIVES AND PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING RESPIRATORY DISEASE OR SARS-COV-2 INFECTION DISEASE, COMPRISING SAME | 동화약품주식회사 | 2022-10-06 | — | — | WO | disclosed |
| CN-101781305-A | Method for artificially synthesizing galanthamine | TAIZHOU JINZHAO WEIYE FINE CHE | 2010-07-21 | — | — | CN | disclosed |
| EP-0819108-B1 | Process for preparing galanthamine derivatives by asymmetric reduction | JANSSEN PHARMACEUTICA NV (BE) | 2001-08-29 | — | — | EP | disclosed |
| US-6018043-A | Process for preparing galanthamine derivatives by asymmetric reduction | JANSSEN PHARMACEUTICA, N.V. (BE) | 2000-01-25 | — | — | US | disclosed |
| EP-0819108-A1 | PROCESS FOR PREPARING GALANTHAMINE DERIVATIVES BY ASYMMETRIC REDUCTION | Chiroscience Limited (GB) | 1998-01-21 | — | — | EP | disclosed |
| WO-1996031453-A1 | PROCESS FOR PREPARING GALANTHAMINE DERIVATIVES BY ASYMMETRIC REDUCTION | CHIROSCIENCE LIMITED (GB) | 1996-10-10 | — | — | WO | disclosed |