Known targets — ChEMBL curated mechanism
MMP1MMP13MMP7MMP8polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Alcohol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BLM | P54132 | 1/20 | 0.58 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.48 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.43 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.43 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.43 |
| ▸ | LTA4H | P09960 | 1/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.40 |
| ▸ | HRH1 | P35367 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12939738 | 0.92 | BLM (0.65) | BLMGABRR1CYP1A2ACE2SLC1A3 | |
| SCHEMBL580558 | 0.92 | BLM (0.65) | BLMGABRR1CYP1A2ACE2SLC1A3 | |
| SCHEMBL27489069 | 0.84 | BLM (0.71) | BLMGABRR1CYP1A2ACE2SLC1A3 | |
| SCHEMBL5139179 | 0.83 | GABRR1 (0.72) | BLMGABRR1CYP1A2ACE2LTA4H | |
| Alcohol SCHEMBL6917476 | 0.80 | CYP1A2 (0.86) | BLMGABRR1CYP1A2ACE2SLC1A3 | |
| SCHEMBL29184102 | 0.80 | BLM (0.53) | BLMGABRR1CYP1A2ACE2SLC1A3 | |
| SCHEMBL891189 | 0.79 | BLM (0.78) | BLMGABRR1CYP1A2ACE2SLC1A3 | |
| SCHEMBL6254815 | 0.79 | BLM (0.86) | BLMGABRR1CYP1A2ACE2SLC1A3 | |
| SCHEMBL13343956 | 0.79 | BLM (0.78) | BLMGABRR1CYP1A2ACE2SLC1A3 | |
| SCHEMBL276749 | 0.79 | BLM (0.86) | BLMGABRR1CYP1A2ACE2SLC1A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20010034966-A1 | Method of reducing the vapor pressure of ethanol-containing motor fuels for spark ignition combustion engines | GOLUBKOV ANGELICA (SE) | 2001-11-01 | — | — | US | disclosed |