Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.60 |
| ▸ | TARDBP | Q13148 | 2/20 | 0.60 |
| ▸ | ACHE | P22303 | 2/20 | 0.60 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.60 |
| ▸ | MEN1 | O00255 | 1/20 | 0.60 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 1/20 | 0.60 |
| ▸ | POLB | P06746 | 1/20 | 0.60 |
| ▸ | THRB | P10828 | 1/20 | 0.60 |
| ▸ | TSHR | P16473 | 1/20 | 0.60 |
| ▸ | APEX1 | P27695 | 1/20 | 0.60 |
| ▸ | RECQL | P46063 | 1/20 | 0.60 |
| ▸ | BLM | P54132 | 1/20 | 0.60 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.60 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.60 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7843950 | 1.00 | HSD17B10 (0.60) | HSD17B10KMT2ATARDBPACHECYP2C9 | |
| SCHEMBL18503015 | 1.00 | HSD17B10 (0.60) | HSD17B10KMT2ATARDBPACHECYP2C9 | |
| SCHEMBL8516625 | 1.00 | HSD17B10 (0.60) | HSD17B10KMT2ATARDBPACHECYP2C9 | |
| SCHEMBL17265764 | 1.00 | HSD17B10 (0.60) | HSD17B10KMT2ATARDBPACHECYP2C9 | |
| SCHEMBL26804183 | 0.89 | HSD17B10 (0.61) | HSD17B10KMT2ATARDBPACHECYP2C9 | |
| SCHEMBL17265752 | 0.89 | HSD17B10 (0.61) | HSD17B10KMT2ATARDBPACHECYP2C9 | |
| SCHEMBL8516693 | 0.89 | HSD17B10 (0.61) | HSD17B10KMT2ATARDBPACHECYP2C9 | |
| SCHEMBL15892712 | 0.87 | KMT2A (0.60) | HSD17B10KMT2ATARDBPACHECYP2C9 | |
| SCHEMBL2378783 | 0.87 | KMT2A (0.60) | HSD17B10KMT2ATARDBPACHECYP2C9 | |
| SCHEMBL7839940 | 0.87 | KMT2A (0.57) | HSD17B10KMT2ATARDBPACHECYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6313164-B1 | TO ENHANCE THE ACTIVITY OF GLUTATHIONE RECLUCTASE; FOR THERAPY AND PROPHYLAXIS OF CARTARACTS | SANKYO COMPANY, LIMITED (JP) | 2001-11-06 | — | — | US | disclosed |
| EP-1070710-A2 | Dithiolan derivatives, their preparation and their therapeutic effect | Sankyo Company Limited (JP) | 2001-01-24 | — | — | EP | disclosed |
| EP-0869126-A1 | Dithiolan derivatives, their preparation and their therapeutic effect | Sankyo Company Limited (JP) | 1998-10-07 | — | — | EP | disclosed |