Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 2/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.33 |
| ▸ | APP | P05067 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 2/20 | 0.30 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7844460 | 1.00 | F10 (0.33) | F10TAAR1APPHTTNR2F2 | |
| SCHEMBL6667972 | 0.76 | TRPV1 (0.40) | MEN1KMT2A | |
| SCHEMBL6198072 | 0.76 | EGLN1 (0.47) | HTTKDM4EMEN1KMT2A | |
| SCHEMBL8124615 | 0.71 | PIK3CA (0.35) | KDM4EMEN1GAAKMT2A | |
| SCHEMBL6199743 | 0.70 | GAA (0.44) | GAA | |
| SCHEMBL1618188 | 0.69 | PARP1 (0.41) | APPHTTKDM4EMEN1KMT2A | |
| SCHEMBL6196111 | 0.67 | EGLN1 (0.47) | HTTKDM4EMEN1KMT2A | |
| SCHEMBL6198849 | 0.65 | EGLN1 (0.51) | HTTKDM4EMEN1KMT2A | |
| SCHEMBL1616605 | 0.64 | MAPK1 (0.53) | KDM4EMEN1GAAKMT2A | |
| SCHEMBL6194761 | 0.64 | POLA1 (0.54) | HTTKDM4EMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140850-A1 | QUINOLINECARBOXAMIDES AS ANTIVIRAL AGENTS | PHARMACIA & UPJOHN COMPANY (US) | 2001-10-10 | — | — | EP | disclosed |
| WO-2000040561-A1 | QUINOLINECARBOXAMIDES AS ANTIVIRAL AGENTS | PHARMACIA & UPJOHN COMPANY (US) | 2000-07-13 | — | — | WO | disclosed |