⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL98305 | 0.97 | — | — | |
| SCHEMBL5795317 | 0.94 | — | — | |
| SCHEMBL12667192 | 0.69 | — | — | |
| SCHEMBL16524987 | 0.69 | — | — | |
| SCHEMBL181757 | 0.69 | — | — | |
| SCHEMBL4601743 | 0.69 | — | — | |
| SCHEMBL18657021 | 0.64 | — | — | |
| SCHEMBL14811958 | 0.57 | — | — | |
| SCHEMBL775329 | 0.57 | — | — | |
| SCHEMBL111715 | 0.51 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0767790-B1 | CONDENSED IMIDAZOLE COMPOUNDS, THEIR PRODUCTION AND USE | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2001-12-12 | — | — | EP | disclosed |
| CN-1046725-C | fused imidazole compounds, their preparation and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1999-11-24 | — | — | CN | disclosed |
| US-5840732-A | ANTIDIABETIC AGENTS, AUTOIMMUNE DISEASES OR IMMUNOSUPPRESSANTS | TAKEDA CHEMICAL INDUSTRIES LTD. (JP) | 1998-11-24 | — | — | US | disclosed |
| CN-1151161-A | fused imidazole compounds, their preparation and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1997-06-04 | — | — | CN | disclosed |
| EP-0767790-A1 | CONDENSED IMIDAZOLE COMPOUNDS, THEIR PRODUCTION AND USE | Takeda Chemical Industries, Ltd. (JP) | 1997-04-16 | — | — | EP | disclosed |
| WO-1995035296-A1 | CONDENSED IMIDAZOLE COMPOUNDS, THEIR PRODUCTION AND USE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1995-12-28 | — | — | WO | disclosed |
| CN-1003445-B | thiazolidinedione derivatives, their preparation and use | 武田药品工业株式会社 | 1989-03-01 | — | — | CN | disclosed |
| CN-85107870-A | The preparation method of thiazolidine diketone derivative and purposes | — | 1986-07-16 | — | — | CN | disclosed |
| US-4411901-A | ANTIPSYCHOTICS | MEAD JOHNSON & COMPANY (US) | 1983-10-25 | — | — | US | disclosed |
| US-4367335-A | PSYCHOLOGICAL DISORDERS | MEAD JOHNSON & COMPANY (US) | 1983-01-04 | — | — | US | disclosed |