⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3304164 | 0.75 | — | — | |
| SCHEMBL19817579 | 0.71 | — | — | |
| SCHEMBL3526921 | 0.69 | — | — | |
| SCHEMBL6692233 | 0.69 | — | — | |
| SCHEMBL13219048 | 0.69 | — | — | |
| SCHEMBL2021124 | 0.65 | — | — | |
| SCHEMBL11758108 | 0.63 | — | — | |
| SCHEMBL9343001 | 0.62 | — | — | |
| SCHEMBL882435 | 0.62 | — | — | |
| SCHEMBL17625218 | 0.60 | GBA1 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4132740-A | Preparation of carboranyl sulfides | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE ARMY (US) | 1979-01-02 | — | — | US | claimed |
| US-9879043-B1 | Synthesis of non-natural cofactor analogs of S-adenosyl-L-methionine using methionine adenosyltransferase | UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION (US) | 2018-01-30 | — | — | US | disclosed |
| US-9879043-B1 | Synthesis of non-natural cofactor analogs of S-adenosyl-L-methionine using methionine adenosyltransferase | UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION (US) | 2018-01-30 | — | — | US | disclosed |
| EP-2185547-B1 | IMIDAZOLONE DERIVATIVES, PREPARATION METHOD THEREOF AND BIOLOGICAL USE OF SAME | UNIV RENNES (FR) | 2017-07-19 | — | — | EP | disclosed |
| US-8563588-B2 | Imidazolone derivatives, method for the preparation thereof and biological applications | UNIVERSITE DE RENNES 1 (FR) | 2013-10-22 | — | — | US | disclosed |
| US-20100216855-A1 | IMIDAZAOLONE DERIVATIVES,PREPARATION THEREOF AND BIOLOGICAL USE OF SAME | UNIVERSITE DE RENNES (FR) | 2010-08-26 | — | — | US | disclosed |
| EP-1077927-A1 | NOVEL SUBSTITUTED CYCLIC COMPOUNDS, PREPARATION METHOD AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | ADIR ET COMPAGNIE (FR) | 2001-02-28 | — | — | EP | disclosed |
| WO-1999058495-A1 | NOVEL SUBSTITUTED CYCLIC COMPOUNDS, PREPARATION METHOD AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | ADIR ET COMPAGNIE (FR) | 1999-11-18 | — | — | WO | disclosed |