⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1806947 | 0.63 | — | — | |
| Bromide SCHEMBL9390069 | 0.62 | — | — | |
| Hydrochloric Acid SCHEMBL28718850 | 0.62 | — | — | |
| SCHEMBL13021206 | 0.55 | — | — | |
| SCHEMBL17734086 | 0.55 | — | — | |
| SCHEMBL28340738 | 0.54 | — | — | |
| SCHEMBL22242116 | 0.54 | — | — | |
| SCHEMBL27898465 | 0.52 | — | — | |
| SCHEMBL15127182 | 0.50 | — | — | |
| SCHEMBL9135975 | 0.49 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0857725-B1 | (N-(pyridinylmethyl)-heterocyclic)-ylideneamine compounds as nicotinic acetylcholine receptor binding agents | PFIZER (US) | 2001-07-25 | — | — | EP | disclosed |
| US-6020335-A | (N-(pyridinylmethyl)-heterocyclic)ylideneamine compounds as nicotinic acetylcholine receptor binding agents | PFIZER INC (US) | 2000-02-01 | — | — | US | disclosed |
| EP-0857725-A1 | (N-(pyridinylmethyl)-heterocyclic)-ylideneamine compounds as nicotinic acetylcholine receptor binding agents | PFIZER INC. (US) | 1998-08-12 | — | — | EP | disclosed |