SCHEMBL7845381

SCHEMBL7845381

[O]C(=O)CCCC(CC(=O)O)C(=O)O

nearest known ligand 0.61

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
FOLH1 Q04609 13/20 0.61
CA2 P00918 1/20 0.39
MAPK1 P28482 1/20 0.39
CPA1 P15085 2/20 0.38
CPB2 Q96IY4 2/20 0.38
CPB1 P15086 1/20 0.38
CPA3 P15088 1/20 0.38
TDP1 Q9NUW8 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2483229 0.86 FOLH1 (0.74) FOLH1
SCHEMBL29217 0.84 FOLH1 (0.68) FOLH1CA2MAPK1CPA1CPB2
SCHEMBL352404 0.81 FOLH1 (0.65) FOLH1CA2MAPK1CPA1CPB2
SCHEMBL158836 0.81 FOLH1 (0.65) FOLH1CA2MAPK1CPA1CPB2
SCHEMBL30719576 0.81 FOLH1 (0.65) FOLH1CA2MAPK1CPA1CPB2
SCHEMBL4651796 0.80 FOLH1 (0.71) FOLH1
SCHEMBL29253382 0.78 FOLH1 (0.68) FOLH1
SCHEMBL27714307 0.78 FOLH1 (0.68) FOLH1
SCHEMBL9064083 0.78 FOLH1 (0.68) FOLH1
SCHEMBL11754709 0.78 FOLH1 (0.68) FOLH1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0719258-B1 CYCLIC AMIDE DERIVATIVES FOR PROTECTING AGAINST ULTRAVIOLET RAYS OTSUKA PHARMA CO LTD (JP) 2001-10-31 EP disclosed
US-5786367-A OXYGEN SCAVENGERS OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1998-07-28 US disclosed
EP-0719258-A1 CYCLIC AMIDE DERIVATIVES FOR PROTECTING AGAINST ULTRAVIOLET RAYS OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1996-07-03 EP disclosed
WO-1996002508-A1 CYCLIC AMIDE DERIVATIVES FOR PROTECTING AGAINST ULTRAVIOLET RAYS OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1996-02-01 WO disclosed