Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7846040 | 0.84 | HSD17B10 (0.43) | TSHRKDM4EHSD17B10MEN1KMT2A | |
| SCHEMBL7835482 | 0.82 | TSHR (0.42) | TSHRKDM4EHSD17B10MEN1KMT2A | |
| SCHEMBL7844966 | 0.81 | HSD17B10 (0.41) | TSHRKDM4EHSD17B10MEN1KMT2A | |
| SCHEMBL7847936 | 0.80 | SPHK2 (0.32) | — | |
| Hydrochloric Acid SCHEMBL7847285 | 0.79 | SPHK2 (0.32) | — | |
| SCHEMBL7845861 | 0.78 | TSHR (0.43) | TSHRKDM4EHSD17B10MEN1KMT2A | |
| SCHEMBL7841724 | 0.77 | TSHR (0.38) | TSHRKDM4EHSD17B10MEN1KMT2A | |
| SCHEMBL8603428 | 0.73 | — | — | |
| SCHEMBL7846436 | 0.70 | HSD17B10 (0.41) | TSHRKDM4EHSD17B10MEN1KMT2A | |
| SCHEMBL7834522 | 0.68 | HSD17B10 (0.39) | TSHRKDM4EHSD17B10MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0767790-B1 | CONDENSED IMIDAZOLE COMPOUNDS, THEIR PRODUCTION AND USE | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2001-12-12 | — | — | EP | disclosed |
| EP-0767790-A1 | CONDENSED IMIDAZOLE COMPOUNDS, THEIR PRODUCTION AND USE | Takeda Chemical Industries, Ltd. (JP) | 1997-04-16 | — | — | EP | disclosed |
| WO-1995035296-A1 | CONDENSED IMIDAZOLE COMPOUNDS, THEIR PRODUCTION AND USE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1995-12-28 | — | — | WO | disclosed |