Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 5/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | CFTR | P13569 | 1/20 | 0.38 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | TACR2 | P21452 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7848149 | 0.95 | POLB (0.42) | POLBSIGMAR1ALDH1A1KDM4EHPGD | |
| SCHEMBL7833923 | 0.86 | CFTR (0.45) | POLBALDH1A1KDM4EHPGDCFTR | |
| SCHEMBL7846548 | 0.86 | CFTR (0.42) | POLBALDH1A1KDM4EHPGDCFTR | |
| SCHEMBL7847436 | 0.84 | KDM4E (0.44) | POLBALDH1A1KDM4EHPGDCFTR | |
| SCHEMBL7842246 | 0.83 | KDM4E (0.44) | POLBALDH1A1KDM4EHPGDCFTR | |
| SCHEMBL7845109 | 0.82 | CFTR (0.42) | POLBALDH1A1KDM4EHPGDCFTR | |
| SCHEMBL7841391 | 0.82 | CFTR (0.41) | POLBALDH1A1KDM4EHPGDCFTR | |
| SCHEMBL7846115 | 0.80 | HSD17B10 (0.42) | POLBALDH1A1KDM4EHPGDCFTR | |
| SCHEMBL7843694 | 0.79 | GAA (0.46) | POLBALDH1A1KDM4EHPGDCFTR | |
| SCHEMBL6670139 | 0.78 | CFTR (0.39) | POLBCFTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140850-A1 | QUINOLINECARBOXAMIDES AS ANTIVIRAL AGENTS | PHARMACIA & UPJOHN COMPANY (US) | 2001-10-10 | — | — | EP | claimed |
| WO-2000040561-A1 | QUINOLINECARBOXAMIDES AS ANTIVIRAL AGENTS | PHARMACIA & UPJOHN COMPANY (US) | 2000-07-13 | — | — | WO | claimed |