SCHEMBL78459

SCHEMBL78459

Fc1[c]c(F)c(F)cc1F

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28232752 0.96
SCHEMBL27779661 0.96
SCHEMBL27634277 0.96
SCHEMBL27961218 0.96
SCHEMBL28779375 0.96
SCHEMBL27464803 0.87
SCHEMBL28446084 0.83
SCHEMBL1392628 0.79
SCHEMBL272519 0.78
SCHEMBL17110647 0.78 KDM1A (0.30)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1633 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240199777-A1 AMINO-BENZIMIDAZOLE CATALYSTS FOR THE PREPARATION OF POLYOLEFINS DOW GLOBAL TECHNOLOGIES LLC (US) 2024-06-20 US claimed
CN-117983300-A Catalyst containing N-triptycene ligand for ethylene selective tetramerization and preparation method and application thereof 华东理工大学 2024-05-07 CN claimed
US-20240082830-A1 TRIARYL BORANE CATALYSTS AND METHOD FOR SELECTIVE HYDROSILYLATION OF ESTERS AND LACTONES USING SAID CATALYSTS ALDEXCHEM KFT. (HU) 2024-03-14 US claimed
EP-4298136-A1 AMINO-BENZIMIDAZOLE CATALYSTS FOR THE PREPARATION OF POLYOLEFINS Dow Global Technologies LLC (US) 2024-01-03 EP claimed
CN-116964110-A Amino-benzimidazole catalysts for preparing polyolefins 陶氏环球技术有限责任公司 2023-10-27 CN claimed
EP-4263560-A1 TRIARYL BORANE CATALYSTS AND METHOD FOR SELECTIVE HYDROSILYLATION OF ESTERS AND LACTONES USING SAID CATALYSTS AldexChem Kft. (HU) 2023-10-25 EP claimed
WO-2022183008-A9 AMINO-BENZIMIDAZOLE CATALYSTS FOR THE PREPARATION OF POLYOLEFINS DOW GLOBAL TECHNOLOGIES LLC (US) 2023-10-12 WO claimed
CN-116685594-A Triarylborane catalysts and methods for selective hydrosilylation of esters and lactones using the same 阿尔迪斯化学有限责任公司 2023-09-01 CN claimed
US-20230183248-A1 PYRROLO[1,2-D][1,2,4]TRIAZINE-2-YL-ACETAMIDES AS INHIBITORS OF THE NLRP3 INFLAMMASOME PATHWAY JANSSEN PHARMACEUTICA NV (BE) 2023-06-15 US claimed
CN-115850000-A Synthetic method of diarylmethane compound 海南大学 2023-03-28 CN claimed
WO-1990008143-A1 FLUORINATED FLAVONE ACETIC ACID THE UPJOHN COMPANY (US) 1990-07-26 WO claimed
US-4889553-A Herbicides SCHERING AGROCHEMICALS (GB) 1989-12-26 US claimed
CN-1034545-A The protein and the glycoprotein of the metal-radioisotope labeling that is used to diagnose and treats NEORX CORP (US) 1989-08-09 CN claimed
EP-0306943-A2 Immunconjugates joined by thioether bonds having reduced toxicity and improved selectivity NEORX CORPORATION (US) 1989-03-15 EP claimed
EP-0160379-B1 2,3,5,6-TETRAFLUOROPHENYL (METH)ACRYLATES AND THEIR PRODUCTION Nippon Shokubai Kagaku Kogyo Co., Ltd (JP) 1988-06-29 EP claimed
EP-0246749-A2 Triazole herbicides AgrEvo UK Limited (GB) 1987-11-25 EP claimed
EP-0174131-A2 Dihydropyridines, processes and intermediates for their production, and pharmaceutical formulations containing them FISONS plc (GB) 1986-03-12 EP claimed
EP-0160379-A1 2,3,5,6-tetrafluorophenyl (meth)acrylates and their production Nippon Shokubai Kagaku Kogyo Co., Ltd (JP) 1985-11-06 EP claimed
US-4264605-A INSECTICIDES ELI LILLY AND COMPANY (US) 1981-04-28 US claimed
EP-0008881-A1 1-Benzoyl-3-pyridinyl ureas, their use as insecticides, their preparation and formulations containing them ELI LILLY AND COMPANY (US) 1980-03-19 EP claimed