Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 3/20 | 0.49 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.49 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.49 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.48 |
| ▸ | FURIN | P09958 | 2/20 | 0.47 |
| ▸ | HRH1 | P35367 | 1/20 | 0.47 |
| ▸ | KDM1A | O60341 | 1/20 | 0.44 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.42 |
| ▸ | FFAR4 | Q5NUL3 | 10/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15574815 | 0.89 | SLC6A2 (0.52) | SLC6A2SLC6A3SLC6A4ROCK1FURIN | |
| SCHEMBL15574816 | 0.89 | SLC6A2 (0.52) | SLC6A2SLC6A3SLC6A4ROCK1FURIN | |
| SCHEMBL15574817 | 0.89 | SLC6A2 (0.52) | SLC6A2SLC6A3SLC6A4ROCK1FURIN | |
| Trifluoroacetic Acid SCHEMBL25284957 | 0.87 | PARP10 (0.43) | SLC6A2SLC6A3SLC6A4ROCK1FURIN | |
| SCHEMBL24969453 | 0.82 | ROCK1 (0.49) | ROCK1FURINPARP10FFAR4 | |
| SCHEMBL20046785 | 0.82 | SLC6A2 (0.57) | SLC6A2SLC6A3SLC6A4HRH1KDM1A | |
| SCHEMBL30182887 | 0.82 | SLC6A2 (0.57) | SLC6A2SLC6A3SLC6A4HRH1KDM1A | |
| SCHEMBL796490 | 0.82 | HRH1 (0.65) | SLC6A2SLC6A3SLC6A4FURINHRH1 | |
| Ammonia Solution, Strong SCHEMBL8081694 | 0.80 | HRH1 (0.63) | SLC6A2SLC6A3SLC6A4FURINHRH1 | |
| SCHEMBL18186080 | 0.78 | BCL2A1 (0.53) | SLC6A2SLC6A3SLC6A4ROCK1FURIN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1115694-A1 | SUBSTITUTED N-ALIPHATIC-N-AROMATIC (TERTIARY)-HETEROALKYLAMINES USEFUL FOR INHIBITING CHOLESTERYL ESTER TRANSFER PROTEIN ACTIVITY | Monsanto Company (US) | 2001-07-18 | — | — | EP | claimed |
| WO-2000018723-A1 | SUBSTITUTED N-ALIPHATIC-N-AROMATIC TERTIARY-HETEROALKYLAMINES USEFUL FOR INHIBITING CHOLESTERYL ESTER TRANSFER PROTEIN ACTIVITY | MONSANTO COMPANY (US) | 2000-04-06 | — | — | WO | claimed |