Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 20/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4827725 | 0.87 | MAPK14 (0.55) | MAPK14 | |
| SCHEMBL4831618 | 0.85 | MAPK14 (0.54) | MAPK14 | |
| SCHEMBL4829504 | 0.80 | MAPK14 (0.61) | MAPK14 | |
| SCHEMBL4824342 | 0.79 | MAPK14 (0.52) | MAPK14 | |
| SCHEMBL5897231 | 0.79 | MAPK14 (0.68) | MAPK14 | |
| SCHEMBL7594290 | 0.79 | MAPK14 (0.77) | MAPK14 | |
| SCHEMBL4831641 | 0.78 | MAPK14 (0.60) | MAPK14 | |
| SCHEMBL5897115 | 0.77 | MAPK14 (0.65) | MAPK14 | |
| SCHEMBL7841389 | 0.76 | MAPK14 (0.71) | MAPK14 | |
| SCHEMBL5897121 | 0.76 | MAPK14 (0.62) | MAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1115707-A1 | BENZAMIDE DERIVATIVES AND THER USE AS CYTOKINE INHIBITORS | AstraZeneca AB (SE) | 2001-07-18 | — | — | EP | disclosed |
| WO-2000018738-A1 | BENZAMIDE DERIVATIVES AND THEIR USE AS CYTOKINE INHIBITORS | ASTRAZENECA AB (SE) | 2000-04-06 | — | — | WO | disclosed |